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Emerg Infect Dis . Spatiotemporal Evolution of SARS-CoV-2 Alpha and Delta Variants during Large Nationwide Outbreak of COVID-19, Vietnam, 2021

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2023 Apr 4;29(5).
doi: 10.3201/eid2905.221787. Online ahead of print.
Spatiotemporal Evolution of SARS-CoV-2 Alpha and Delta Variants during Large Nationwide Outbreak of COVID-19, Vietnam, 2021

Nguyen Thi Tam, Nguyen To Anh, Trinh Son Tung, Pham Ngoc Thach, Nguyen Thanh Dung, Van Dinh Trang, Le Manh Hung, Trinh Cong Dien, Nghiem My Ngoc, Le Van Duyet, Phan Manh Cuong, Hoang Vu Mai Phuong, Pham Quang Thai, Nguyen Le Nhu Tung, Dinh Nguyen Huy Man, Nguyen Thanh Phong, Vo Minh Quang, Pham Thi Ngoc Thoa, Nguyen Thanh Truong, Tran Nguyen Phuong Thao, Dao Phuong Linh, Ngo Tan Tai, Ho The Bao, Vo Trong Vuong, Huynh Thi Kim Nhung, Phan Nu Dieu Hong, Le Thi Phuoc Hanh, Le Thanh Chung, Nguyen Thi Thanh Nhan, Ton That Thanh, Do Thai Hung, Huynh Kim Mai, Trinh Hoang Long, Nguyen Thu Trang, Nguyen Thi Hong Thuong, Nguyen Thi Thu Hong, Le Nguyen Truc Nhu, Nguyen Thi Han Ny, Cao Thu Thuy, Le Kim Thanh, Lam Anh Nguyet, Le Thi Quynh Mai, Tang Chi Thuong, Le Hong Nga, Tran Tan Thanh, Guy Thwaites, H Rogier van Doorn, Nguyen Van Vinh Chau, Thomas Kesteman, Le Van Tan; OUCRU COVID-19 Research Groups2

Abstract

We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions.

Keywords: Alpha variant; COVID-19; Delta variant; SARS-CoV-2; Vietnam; coronavirus disease; coronaviruses; outbreak; respiratory infections; severe acute respiratory syndrome coronavirus-2; spatiotemporal evolution; viruses; zoonoses.
 
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