tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2024 May;30(5):1050-1052.
doi: 10.3201/eid3005.231739.
SARS-CoV-2 IgG Levels as Predictors of XBB Variant Neutralization, Israel, 2022- and 2023
Yaniv Lustig, Michal Canetti, Victoria Indenbaum, Yovel Peretz, Yael Weiss-Ottolenghi, Ili Margalit, Keren Asraf, Tal Levin, Neta Zuckerman, Enosh Tomer, Michal Mandelboim, Ram Doolman, Noam Barda, Gili Regev-Yochay
Although a vaccine against SARS-CoV-2 Omicron-XBB.1.5 variant is available worldwide and recent infection is protective, the lack of recorded infection data highlights the need to assess variant-specific antibody neutralization levels. We analyzed IgG levels against receptor-binding domain-specific SARS-CoV-2 ancestral strain as a correlate for high neutralizing titers against XBB variants.
Keywords: COVID-19; IgG; Israel; SARS-CoV-2; XBB variant; antibodies; neutralizing antibodies; respiratory infections; vaccine-preventable diseases; vaccines; viruses.
. 2024 May;30(5):1050-1052.
doi: 10.3201/eid3005.231739.
SARS-CoV-2 IgG Levels as Predictors of XBB Variant Neutralization, Israel, 2022- and 2023
Yaniv Lustig, Michal Canetti, Victoria Indenbaum, Yovel Peretz, Yael Weiss-Ottolenghi, Ili Margalit, Keren Asraf, Tal Levin, Neta Zuckerman, Enosh Tomer, Michal Mandelboim, Ram Doolman, Noam Barda, Gili Regev-Yochay
- PMID: 38666742
- DOI: 10.3201/eid3005.231739
Although a vaccine against SARS-CoV-2 Omicron-XBB.1.5 variant is available worldwide and recent infection is protective, the lack of recorded infection data highlights the need to assess variant-specific antibody neutralization levels. We analyzed IgG levels against receptor-binding domain-specific SARS-CoV-2 ancestral strain as a correlate for high neutralizing titers against XBB variants.
Keywords: COVID-19; IgG; Israel; SARS-CoV-2; XBB variant; antibodies; neutralizing antibodies; respiratory infections; vaccine-preventable diseases; vaccines; viruses.