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Emerg Infect Dis . Omicron BA.5 Neutralization among Vaccine-Boosted Persons with Prior Omicron BA.1/BA.2 Infections

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2022 Nov 8;28(12).
doi: 10.3201/eid2812.221304. Online ahead of print.
Omicron BA.5 Neutralization among Vaccine-Boosted Persons with Prior Omicron BA.1/BA.2 Infections

Rune M Pedersen, Line L Bang, Ditte S Tornby, Lone W Madsen, Dorte K Holm, Thomas V Sydenham, Isik S Johansen, Thøger G Jensen, Ulrik S Justesen, Thomas E Andersen

Abstract

Worldwide, millions of persons have received multiple COVID-19 vaccinations and subsequently recovered from SARS-CoV-2 Omicron breakthrough infections. In 2 small, matched cohorts (n = 12, n = 24) in Denmark, we found Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provided improved Omicron BA.5 neutralization over 3-dose vaccination alone.

Keywords: BA.1; BA.2; BA.5; COVID-19; Omicron; SARS; SARS-CoV-2; coronavirus; coronavirus disease; respiratory infections; severe acute respiratory syndrome coronavirus 2; vaccines; viruses; zoonoses.
 
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