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Emerg Infect Dis . Multisystem Inflammatory Syndrome in Adult after First Dose of mRNA Vaccine

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2022 Feb 11;28(4).
doi: 10.3201/eid2804.212585. Online ahead of print.
Multisystem Inflammatory Syndrome in Adult after First Dose of mRNA Vaccine

Yusuke Miyazato, Kei Yamamoto, Gen Yamada, Shuji Kubota, Masahiro Ishikane, Masaya Sugiyama, Mikako Ueno, Akihiro Matsunaga, Tohru Miyoshi-Akiyama, Yukihito Ishizaka, Norio Ohmagari
Free article

Abstract

A 32-year-old man in Japan experienced respiratory failure after receiving the first dose of coronavirus disease (COVID-19) vaccine. He was treated with noninvasive ventilation and corticosteroids. Serologic test results suggested previous COVID-19; therefore, he received a diagnosis of multisystem inflammatory syndrome. COVID-19 vaccination could be a trigger for this condition.

Keywords: COVID-19; Japan; MIS-A; SARS-CoV-2; anti-nucleocapsid antibody; anti-spike antibody; coronavirus disease; cytokine profile; hyperinflammatory state; multisystem inflammatory syndrome; myocardial injury; respiratory failure; severe acute respiratory syndrome coronavirus 2; vaccination.
 
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