Giuseppe
Emeritus
[Source: Emerging Infectious Diseases Journal, full text: (LINK). Abstract, edited.]
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Dispatch
Fatal Respiratory Infections Associated with Rhinovirus Outbreak, Vietnam
Le Thanh Hai, Vu Thi Ngoc Bich, Le Kien Ngai, Nguyen Thi Ngoc Diep, Phan Huu Phuc, Viet Pham Hung, Walter R. Taylor, Peter Horby, Nguyen Thanh Liem, and Heiman F.L. Wertheim
Author affiliations: National Hospital of Pediatrics, Hanoi, Vietnam (L.T. Hai, L.K. Ngai, P.H. Phuc, V.P. Hung, N.T. Liem); Wellcome Trust Major Overseas Program Vietnam, Hanoi (V.T.N. Bich, N.T.N. Diep, W.R. Taylor, P. Horby, H.F.L. Wertheim); Oxford University Clinical Research Unit, Hanoi (W.R. Taylor, P. Horby, H.F.L. Wertheim); and University of Oxford, Oxford, UK (W.R. Taylor, P. Horby, H.F.L. Wertheim)
Abstract
During an outbreak of severe acute respiratory infections in 2 orphanages, Vietnam, 7/12 hospitalized children died. All hospitalized children and 26/43 children from outbreak orphanages tested positive for rhinovirus versus 9/40 control children (p = 0.0005). Outbreak rhinoviruses formed a distinct genetic cluster. HRV is an underappreciated cause of severe pneumonia in vulnerable groups.
-Fatal Respiratory Infections Associated with Rhinovirus Outbreak, Vietnam
Le Thanh Hai, Vu Thi Ngoc Bich, Le Kien Ngai, Nguyen Thi Ngoc Diep, Phan Huu Phuc, Viet Pham Hung, Walter R. Taylor, Peter Horby, Nguyen Thanh Liem, and Heiman F.L. Wertheim
Author affiliations: National Hospital of Pediatrics, Hanoi, Vietnam (L.T. Hai, L.K. Ngai, P.H. Phuc, V.P. Hung, N.T. Liem); Wellcome Trust Major Overseas Program Vietnam, Hanoi (V.T.N. Bich, N.T.N. Diep, W.R. Taylor, P. Horby, H.F.L. Wertheim); Oxford University Clinical Research Unit, Hanoi (W.R. Taylor, P. Horby, H.F.L. Wertheim); and University of Oxford, Oxford, UK (W.R. Taylor, P. Horby, H.F.L. Wertheim)
Abstract
During an outbreak of severe acute respiratory infections in 2 orphanages, Vietnam, 7/12 hospitalized children died. All hospitalized children and 26/43 children from outbreak orphanages tested positive for rhinovirus versus 9/40 control children (p = 0.0005). Outbreak rhinoviruses formed a distinct genetic cluster. HRV is an underappreciated cause of severe pneumonia in vulnerable groups.
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