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Emerg Infect Dis . Estimates of SARS-CoV-2 Hospitalization and Fatality Rates in the Prevaccination Period, United States

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2024 Jun;30(6):1144-1153.
doi: 10.3201/eid3006.231285.
Estimates of SARS-CoV-2 Hospitalization and Fatality Rates in the Prevaccination Period, United States

Isabel Griffin, Jessica King, B Casey Lyons, Alyson L Singleton, Xidong Deng, Beau B Bruce, Patricia M Griffin
Abstract

Few precise estimates of hospitalization and fatality rates from COVID-19 exist for naive populations, especially within demographic subgroups. We estimated rates among persons with SARS-CoV-2 infection in the United States during May 1-December 1, 2020, before vaccines became available. Both rates generally increased with age; fatality rates were highest for persons >85 years of age (24%) and lowest for children 1-14 years of age (0.01%). Age-adjusted case hospitalization rates were highest for African American or Black, not Hispanic persons (14%), and case-fatality rates were highest for Asian or Pacific Islander, not Hispanic persons (4.4%). Eighteen percent of hospitalized patients and 44.2% of those admitted to an intensive care unit died. Male patients had higher hospitalization (6.2% vs. 5.2%) and fatality rates (1.9% vs. 1.5%) than female patients. These findings highlight the importance of collecting surveillance data to devise appropriate control measures for persons in underserved racial/ethnic groups and older adults.

Keywords: 2019 novel coronavirus disease; COVID-19; SARS-CoV-2; United States; hospitalization; severe acute respiratory syndrome coronavirus 2; vaccine-preventable diseases; viruses.

 
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