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Emerg Infect Dis . Detection of Divergent Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus, São Paulo, Brazil, 2025

tetano

Editor, Senior Moderator
Emerg Infect Dis

. 2026 Oct;32(10):1707-1711.
doi: 10.3201/eid3210.260723.

Detection of Divergent Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus, São Paulo, Brazil, 2025​


Jansen de Araujo, Luciano M Thomazelli, Thomas P Fabrizio, Gustavo O Fenner, Erick G Dorlass, Ana K A Eisen, Viviane F Botosso, Marcello S Nardi, Caroline C Aires, Sergio M N Teixeira, Roberta M de Azevedo, Mayra H Frediani, Tatiana Ometto, Mário G L Barboza, Edmarcia E de Souza, Carsten Wrenger, Richard J Webby, Edison L Durigon



Free article

Abstract​


In 2025, we detected highly pathogenic avian influenza H5N1 virus in dead waterfowl at Ibirapuera Park, São Paulo, Brazil. Genomic characterization indicated a reassortant virus that emerged from locally circulating low pathogenicity avian influenza viruses and highly pathogenic North American lineages. Our results highlight cross-species transmission risk and underscore the need for enhanced surveillance.

Keywords: Brazil; H5N1; Influenza; genomic surveillance; highly pathogenic avian influenza; viral; viruses.
 
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