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Emerg Infect Dis Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2020 May 20;26(8).
doi: 10.3201/eid2608.201843. Online ahead of print.
Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination

Ramona M?gling, Adam Meijer, Natasa Berginc, Sylvia Bruisten, Remi Charrel, Bruno Coutard, Isabella Eckerle, Vincent Enouf, Olav Hungnes, G?lay Korukluoglu, Thanos Kossyvakis, Andreas Mentis, Richard Molenkamp, Shaman Muradrasoli, Anna Papa, Fiona Pigny, Laurence Thirion, Sylvie van der Werf, Chantal Reusken

Abstract

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) created an exceptional situation in which numerous laboratories in Europe simultaneously implemented SARS-CoV-2 diagnostics. These laboratories reported in February 2020 that commercial primer and probe batches for SARS-CoV-2 detection were contaminated with synthetic control material, causing delays of regional testing roll-out in various countries.

Keywords: COVID-19; Europe; PCR; SARS-CoV-2; commercial nucleotide production; contamination; coronavirus disease; coronaviruses; delayed laboratory response; molecular diagnostics; primers; probes; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.
 
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