tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2021 Jul;27(7):1953-1957.
doi: 10.3201/eid2707.204593.
Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020
Teena Mohan, Ha T Nguyen, Krista Kniss, Vasiliy P Mishin, Angiezel A Merced-Morales, Jennifer Laplante, Kirsten St George, Patricia Blevins, Anton Chesnokov, Juan A De La Cruz, Rebecca Kondor, David E Wentworth, Larisa V Gubareva
Abstract
Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the necessity to monitor both drug resistance and antigenic drift of circulating viruses.
Keywords: Texas; United States; antigenic drift; antimicrobial resistance; drug resistance; influenza; influenza A(H1N1); neuraminidase inhibitor; transmission; viruses.
. 2021 Jul;27(7):1953-1957.
doi: 10.3201/eid2707.204593.
Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020
Teena Mohan, Ha T Nguyen, Krista Kniss, Vasiliy P Mishin, Angiezel A Merced-Morales, Jennifer Laplante, Kirsten St George, Patricia Blevins, Anton Chesnokov, Juan A De La Cruz, Rebecca Kondor, David E Wentworth, Larisa V Gubareva
- PMID: 34152954
- DOI: 10.3201/eid2707.204593
Abstract
Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the necessity to monitor both drug resistance and antigenic drift of circulating viruses.
Keywords: Texas; United States; antigenic drift; antimicrobial resistance; drug resistance; influenza; influenza A(H1N1); neuraminidase inhibitor; transmission; viruses.