Giuseppe
Emeritus
Carbapenemases in Enterobacteria, Hong Kong, China, 2009 (Emerg Infect Dis., extract, edited)
[Source: US Centers for Disease Control and Prevention, Emerging Infectious Diseases Journal, full PDF document, (LINK). Extract, edited.]
DOI: 10.3201/eid1701.101443
Suggested citation for this article: Chu Y-W, Tung VWN, Cheung TKM, Chu M-Y, Cheng N, Lai C, et al. Carbapenemases in enterobacteria, Hong Kong, China, 2009 [letter]. Emerg Infect Dis. 2011 Jan; [Epub ahead of print]
Carbapenemases in Enterobacteria, Hong Kong, China, 2009
To the Editor:
Carbapenems are often the recommended treatment for serious infections caused by extended-spectrum β-lactamase?producing enterobacteria. However, enzyme-mediated carbapenem resistance is increasingly reported worldwide. Carbapenemases are represented by 3 molecular classes of β-lactamase: A, B, and D (1). The best known class A carbapenemase is Klebsiella pneumoniae carbapenemase (KPC); KPC-producing enterobacteria are responsible for many hospital outbreaks. Class B carbapenemases are metallo-β-lactamases (MBL), which have the widest substrate spectrum. Class D OXA-type carbapenemases are found mainly in nonfermenting bacteria, except for OXA-48, which has been found only in enterobacteria.
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[Source: US Centers for Disease Control and Prevention, Emerging Infectious Diseases Journal, full PDF document, (LINK). Extract, edited.]
DOI: 10.3201/eid1701.101443
Suggested citation for this article: Chu Y-W, Tung VWN, Cheung TKM, Chu M-Y, Cheng N, Lai C, et al. Carbapenemases in enterobacteria, Hong Kong, China, 2009 [letter]. Emerg Infect Dis. 2011 Jan; [Epub ahead of print]
Carbapenemases in Enterobacteria, Hong Kong, China, 2009
To the Editor:
Carbapenems are often the recommended treatment for serious infections caused by extended-spectrum β-lactamase?producing enterobacteria. However, enzyme-mediated carbapenem resistance is increasingly reported worldwide. Carbapenemases are represented by 3 molecular classes of β-lactamase: A, B, and D (1). The best known class A carbapenemase is Klebsiella pneumoniae carbapenemase (KPC); KPC-producing enterobacteria are responsible for many hospital outbreaks. Class B carbapenemases are metallo-β-lactamases (MBL), which have the widest substrate spectrum. Class D OXA-type carbapenemases are found mainly in nonfermenting bacteria, except for OXA-48, which has been found only in enterobacteria.
(...)
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