tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2024 Jan;30(1):168-171.
doi: 10.3201/eid3001.230756.
Avian Influenza A(H5N1) Neuraminidase Inhibition Antibodies in Healthy Adults after Exposure to Influenza A(H1N1)pdm09
Pavithra Daulagala, Samuel M S Cheng, Alex Chin, Leo L H Luk, Kathy Leung, Joseph T Wu, Leo L M Poon, Malik Peiris, Hui-Ling Yen
We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, antibodies at low titers were detected in 42% (21/50) of serum samples collected in 2009. Influenza A(H1N1)pdm09 and A(H5N1) titers were correlated.
Keywords: clade 2.3.4.4.b; cross-reactive antibody response; influenza; influenza A(H1N1)pdm09; influenza A(H5N1); neuraminidase inhibition antibody; pandemic risk assessment; respiratory infections; viruses.
. 2024 Jan;30(1):168-171.
doi: 10.3201/eid3001.230756.
Avian Influenza A(H5N1) Neuraminidase Inhibition Antibodies in Healthy Adults after Exposure to Influenza A(H1N1)pdm09
Pavithra Daulagala, Samuel M S Cheng, Alex Chin, Leo L H Luk, Kathy Leung, Joseph T Wu, Leo L M Poon, Malik Peiris, Hui-Ling Yen
- PMID: 38147510
- DOI: 10.3201/eid3001.230756
We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, antibodies at low titers were detected in 42% (21/50) of serum samples collected in 2009. Influenza A(H1N1)pdm09 and A(H5N1) titers were correlated.
Keywords: clade 2.3.4.4.b; cross-reactive antibody response; influenza; influenza A(H1N1)pdm09; influenza A(H5N1); neuraminidase inhibition antibody; pandemic risk assessment; respiratory infections; viruses.