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Emerg Infect Dis. All-Cause Mortality during First Wave of Pandemic (H1N1) 2009, New South Wales, Australia, 2009

Giuseppe

Emeritus
All-Cause Mortality, New South Wales, Australia (Emerg Infect Dis., abstract, edited)


[Source: Emerging Infectious Diseases Journal, <cite cite="http://www.cdc.gov/eid/content/16/9/1396.htm">All-Cause Mortality, New South Wales, Australia | CDC EID</cite>. Abstract, edited.]

All-Cause Mortality during First Wave of Pandemic (H1N1) 2009, New South Wales, Australia, 2009

David J. Muscatello, Michelle A. Cretikos, and C. Raina MacIntyre

Author affiliations: New South Wales Department of Health, North Sydney, New South Wales, Australia (D.J. Muscatello, M.A. Cretikos); University of New South Wales, Kensington, New South Wales, Australia (D.J. Muscatello, C.R. MacIntyre); and University of Sydney, Sydney, New South Wales, Australia (M.A. Cretikos)


Abstract

In temperate countries, death rates increase in winter, but influenza epidemics often cause greater increases. The death rate time series that occurs without epidemic influenza can be called a seasonal baseline. Differentiating observed death rates from the seasonally oscillating baseline provides estimated influenza-associated death rates. During 2003?2009 in New South Wales, Australia, we used a Serfling approach with robust regression to estimate age-specific weekly baseline all-cause death rates. Total differences between weekly observed and baseline rates during May?September provided annual estimates of influenza-associated death rates. In 2009, which included our first wave of pandemic (H1N1) 2009, the all-age death rate was 6.0 (95% confidence interval 3.1?8.9) per 100,000 persons lower than baseline. In persons ≥80 years of age, it was 131.6 (95% confidence interval 126.2?137.1) per 100,000 lower. This estimate is consistent with a pandemic virus causing mild illness in most persons infected and sparing older persons.

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