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Elderly-onset acute necrotizing encephalopathy mimicking severe heat stroke: a case report and review of the literature

tetano

Editor, Senior Moderator
Acute Med Surg. 2019 Apr 11;6(3):316-320. doi: 10.1002/ams2.418. eCollection 2019 Jul.
[h=1]Elderly-onset acute necrotizing encephalopathy mimicking severe heat stroke: a case report and review of the literature.[/h] Odagiri A[SUP]1[/SUP], Yamaoka A[SUP]1,[/SUP][SUP]2[/SUP], Miyata K[SUP]2,[/SUP][SUP]3[/SUP], Bunya N[SUP]3[/SUP], Kasai T[SUP]1[/SUP], Takeyama Y[SUP]1[/SUP], Uemura S[SUP]3[/SUP], Mikami T[SUP]2[/SUP], Narimatsu E[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]Background:[/h] Acute necrotizing encephalopathy (ANE), known as influenza-associated encephalitis, typically affects children.
[h=4]Case presentation:[/h] A 70-year-old woman was admitted to the hospital with altered consciousness, a high temperature, and severe hypotension. Computed tomography (CT) of the head showed no abnormalities; thus, a diagnosis of suspected severe heat stroke was made. On day 2, repeated head CT revealed bilateral symmetrical lesions to the thalamus, and a rapid influenza antigen test was positive. Based on the CT findings and the medical history of influenza, a differential diagnosis of ANE was made. Subsequently, brain edema spread across the whole brain, and the patient died on day 21.
[h=4]Conclusion:[/h] In elderly patients, differentiating ANE from severe heat stroke in a high-temperature environment is difficult because of the similarities in clinical symptoms due to multiple organ failure.


[h=4]KEYWORDS:[/h] Bilateral symmetrical thalamic lesions; hyperthermia; influenza‐associated encephalopathy

PMID: 31304037 PMCID: PMC6603324 DOI: 10.1002/ams2.418
 
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