tetano
Editor, Senior Moderator
J Appl Microbiol. 2013 Nov 11. doi: 10.1111/jam.12390. [Epub ahead of print]
Effects of Lactobacillus acidophilus and inulin on fecal viral shedding and immunization against H9 N2 Avian influenza virus.
Poorbaghi SL, Dadras H, Gheisari HR, Mosleh N, Firouzi S, Roohallazadeh H.
Source
Department of Avian Medicine, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Abstract
AIMS:
The aims of this investigation were to compare the effects of Lactobacillus acidophilus addition as simple or microencapsulated (ME) probiotic and inulin as prebiotic to the broiler diet on the fecal viral shedding and immunization against Avian influenza virus (AIV) with or without H9 N2 vaccination.
METHODS AND RESULTS:
Simple or ME forms of Lactobacillus acidophilus, inulin and combination of them as synbiotic were analyzed for their ability to enhance immunity against H9 N2 AIV and to decrease fecal viral shedding in Cobb-500 broiler chicks. Our results indicated that probiotic as ME form can decrease heamagglutination inhibition (HI) titer significantly on days 34 in vaccinated trial (P < 0.05). Also the effects of ME form of probiotic are more remarkable on reduction of viral fecal shedding detected by RT-PCR.
CONCLUSIONS:
The study shows the significant role of microencapsulation on probiotic effects against H9 N2 AIV.
SIGNIFICANCE AND IMPACT OF STUDY:
The application of probiotics especially in the ME form could have the potential for stimulating the immune system, preventing influenza infection and consequently reduce fecal viral shedding of H9 N2 AIV. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Lactobacillus acidophilus , avian influenza, inulin, microencapsulation, prebiotic, probiotic
PMID:
24206196
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24206196
Effects of Lactobacillus acidophilus and inulin on fecal viral shedding and immunization against H9 N2 Avian influenza virus.
Poorbaghi SL, Dadras H, Gheisari HR, Mosleh N, Firouzi S, Roohallazadeh H.
Source
Department of Avian Medicine, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Abstract
AIMS:
The aims of this investigation were to compare the effects of Lactobacillus acidophilus addition as simple or microencapsulated (ME) probiotic and inulin as prebiotic to the broiler diet on the fecal viral shedding and immunization against Avian influenza virus (AIV) with or without H9 N2 vaccination.
METHODS AND RESULTS:
Simple or ME forms of Lactobacillus acidophilus, inulin and combination of them as synbiotic were analyzed for their ability to enhance immunity against H9 N2 AIV and to decrease fecal viral shedding in Cobb-500 broiler chicks. Our results indicated that probiotic as ME form can decrease heamagglutination inhibition (HI) titer significantly on days 34 in vaccinated trial (P < 0.05). Also the effects of ME form of probiotic are more remarkable on reduction of viral fecal shedding detected by RT-PCR.
CONCLUSIONS:
The study shows the significant role of microencapsulation on probiotic effects against H9 N2 AIV.
SIGNIFICANCE AND IMPACT OF STUDY:
The application of probiotics especially in the ME form could have the potential for stimulating the immune system, preventing influenza infection and consequently reduce fecal viral shedding of H9 N2 AIV. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Lactobacillus acidophilus , avian influenza, inulin, microencapsulation, prebiotic, probiotic
PMID:
24206196
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24206196