tetano
Editor, Senior Moderator
Iran J Vet Res. 2016 Fall;17(4):268-272.
[h=1]Effects of dietary supplementation of mannan-oligosaccharide on virus shedding in avian influenza (H9N2) challenged broilers.[/h] Akhtar T[SUP]1[/SUP], Ara G[SUP]2[/SUP], Ali N[SUP]3[/SUP], Ud Din Mufti F[SUP]4[/SUP], Imran Khan M[SUP]5[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Avian influenza (AI) is a highly contagious disease causing significant economic losses worldwide. The aim of this study is to evaluate the effect of mannan-oligosaccharide (MOS) on tracheal and cloacal virus shedding in AI challenged broilers and contamination of environment with H[SUB]9[/SUB]N[SUB]2[/SUB]. A total of 300 1-day-old-broiler chicks were randomly divided into 3 groups (A, B and C) and supplemented 0.2, 0.5 and 0.0% MOS, respectively in NRC recommended diet for 36 days. On day 21 the groups were further split into two sub groups A+ve, A-ve, B+ve, B-ve, C+ve and C-ve with 5 replicates each. The positive groups were shifted to remote sheds and were challenged intranasally with 0.1 ml of reference virus (AIV; Pk-UDL/01/08 H[SUB]9[/SUB]N[SUB]2[/SUB]) with EID[SUB]50[/SUB] = 10[SUP]-6.66[/SUP]. Treatment reduces (P<0.05) cloacal virus shedding from day 24 to 26 and 28 to 32. Tracheal virus shedding was lower (P<0.05) on days 25-26 and 28-30 in treatment groups. Day 27 showed highest (P>0.05) virus shedding in all groups. However the reduction of viral shedding is faster in treatment groups and showed no virus shedding on day 32. Maternal antibody titer against AI showed a declining pattern but MOS influenced (P<0.05) the titer in treated groups. Hence the use of MOS may constitute a novel and effective plausible alternative that reduces the spread of disease by decreasing virus shedding and contamination of environment from AIV (H[SUB]9[/SUB]N[SUB]2[/SUB]) infection in poultry.
[h=4]KEYWORDS:[/h] Avian influenza; Broiler; MOS; SAF-Mannan
PMID: 28224012
[PubMed - in process]
[h=1]Effects of dietary supplementation of mannan-oligosaccharide on virus shedding in avian influenza (H9N2) challenged broilers.[/h] Akhtar T[SUP]1[/SUP], Ara G[SUP]2[/SUP], Ali N[SUP]3[/SUP], Ud Din Mufti F[SUP]4[/SUP], Imran Khan M[SUP]5[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Avian influenza (AI) is a highly contagious disease causing significant economic losses worldwide. The aim of this study is to evaluate the effect of mannan-oligosaccharide (MOS) on tracheal and cloacal virus shedding in AI challenged broilers and contamination of environment with H[SUB]9[/SUB]N[SUB]2[/SUB]. A total of 300 1-day-old-broiler chicks were randomly divided into 3 groups (A, B and C) and supplemented 0.2, 0.5 and 0.0% MOS, respectively in NRC recommended diet for 36 days. On day 21 the groups were further split into two sub groups A+ve, A-ve, B+ve, B-ve, C+ve and C-ve with 5 replicates each. The positive groups were shifted to remote sheds and were challenged intranasally with 0.1 ml of reference virus (AIV; Pk-UDL/01/08 H[SUB]9[/SUB]N[SUB]2[/SUB]) with EID[SUB]50[/SUB] = 10[SUP]-6.66[/SUP]. Treatment reduces (P<0.05) cloacal virus shedding from day 24 to 26 and 28 to 32. Tracheal virus shedding was lower (P<0.05) on days 25-26 and 28-30 in treatment groups. Day 27 showed highest (P>0.05) virus shedding in all groups. However the reduction of viral shedding is faster in treatment groups and showed no virus shedding on day 32. Maternal antibody titer against AI showed a declining pattern but MOS influenced (P<0.05) the titer in treated groups. Hence the use of MOS may constitute a novel and effective plausible alternative that reduces the spread of disease by decreasing virus shedding and contamination of environment from AIV (H[SUB]9[/SUB]N[SUB]2[/SUB]) infection in poultry.
[h=4]KEYWORDS:[/h] Avian influenza; Broiler; MOS; SAF-Mannan
PMID: 28224012
[PubMed - in process]