tetano
Editor, Senior Moderator
Rev Esp Salud Publica. 2019 Apr 29;93. pii: e201904024.
[h=1][Effectiveness of annual flu vaccination until week four of season 2018/2019].[/h] [Article in Spanish; Abstract available in Spanish from the publisher]
Gras-Valent? P[SUP]1[/SUP], Algado-Sell?s N[SUP]1[/SUP], Chico-S?nchez P[SUP]1[/SUP], Cabrera-Tejada GG[SUP]1[/SUP], Rodr?guez-D?az JC[SUP]2[/SUP], S?nchez-Pay? J[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] in English, Spanish
[h=4]OBJECTIVE:[/h] Annual flu vaccination is the most effective measure to prevent the disease and its complications. Vaccine effectiveness (EV) varies from season to season, requiring annual re-evaluation. The objective of this work was to estimate the preliminary effectiveness of the influenza vaccine until epidemiological week 4 of the 2018/2019 season, in patients admitted to a third level hospital.
[h=4]METHODS:[/h] The Test Negative Design (TDN) was carried out at the Hospital General Universitario de Alicante. Patients admitted with laboratory-confirmed influenza (RT-PCR positive for any influenza virus, in clinical sample of nasopharyngeal aspirate) and those with clinical suspicion of influenza and negative RT-PCR, from week 40 to week 4 of the 2018/2019 influenza season, were considered as controls. The vaccination coverage was calculated in the cases and in the controls, and the EV with its 95% confidence interval using the formula: EV = (1-Odds Ratio) x 100.
[h=4]RESULTS:[/h] We included 524 patients: 58 cases and 466 controls. The overall EV for prevention of influenza cases was 42.5 % (95% CI -17.1 to 71.8) and for those over 1 year of age 63.7 % (95% CI 25.4 to 82.3).
[h=4]CONCLUSIONS:[/h] The 2018-2019 influenza vaccine is effective in preventing influenza cases in patients admitted up to week 4 of the 2018-19 season. Results are preliminary and may vary and should be re-evaluated at the end of the season.
[h=4]KEYWORDS:[/h] Human; Influenza; Influenza vaccines; Spain; Treatment outcome; Vaccination; Vaccination coverage
PMID: 31032821
[h=1][Effectiveness of annual flu vaccination until week four of season 2018/2019].[/h] [Article in Spanish; Abstract available in Spanish from the publisher]
Gras-Valent? P[SUP]1[/SUP], Algado-Sell?s N[SUP]1[/SUP], Chico-S?nchez P[SUP]1[/SUP], Cabrera-Tejada GG[SUP]1[/SUP], Rodr?guez-D?az JC[SUP]2[/SUP], S?nchez-Pay? J[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] in English, Spanish
[h=4]OBJECTIVE:[/h] Annual flu vaccination is the most effective measure to prevent the disease and its complications. Vaccine effectiveness (EV) varies from season to season, requiring annual re-evaluation. The objective of this work was to estimate the preliminary effectiveness of the influenza vaccine until epidemiological week 4 of the 2018/2019 season, in patients admitted to a third level hospital.
[h=4]METHODS:[/h] The Test Negative Design (TDN) was carried out at the Hospital General Universitario de Alicante. Patients admitted with laboratory-confirmed influenza (RT-PCR positive for any influenza virus, in clinical sample of nasopharyngeal aspirate) and those with clinical suspicion of influenza and negative RT-PCR, from week 40 to week 4 of the 2018/2019 influenza season, were considered as controls. The vaccination coverage was calculated in the cases and in the controls, and the EV with its 95% confidence interval using the formula: EV = (1-Odds Ratio) x 100.
[h=4]RESULTS:[/h] We included 524 patients: 58 cases and 466 controls. The overall EV for prevention of influenza cases was 42.5 % (95% CI -17.1 to 71.8) and for those over 1 year of age 63.7 % (95% CI 25.4 to 82.3).
[h=4]CONCLUSIONS:[/h] The 2018-2019 influenza vaccine is effective in preventing influenza cases in patients admitted up to week 4 of the 2018-19 season. Results are preliminary and may vary and should be re-evaluated at the end of the season.
[h=4]KEYWORDS:[/h] Human; Influenza; Influenza vaccines; Spain; Treatment outcome; Vaccination; Vaccination coverage
PMID: 31032821