tetano
Editor, Senior Moderator
Clin Vaccine Immunol. 2013 Apr 10. [Epub ahead of print]
Effectiveness of 2010-2011 seasonal influenza vaccine for preventing laboratory-confirmed influenza infection in Korean adult population: Case-control study.
Choi WS, Noh JY, Seo YB, Baek JH, Lee J, Song JY, Park DW, Lee JS, Cheong HJ, Kim WJ.
Source
Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul.
Abstract
We evaluated the effectiveness of the 2010-2011 seasonal influenza vaccine for preventing laboratory-confirmed influenza in a Korean population. A retrospective case-control study was conducted among patients who visited selected hospitals from September 2010 to May 2011. A total of 483 laboratory-confirmed influenza patients were included in the analysis as case subjects. For each case patient, two types of control patients were chosen at a ratio of 1:1:1 and 966 control subjects were selected. Vaccine effectiveness (VE) was defined as [100 ? (1-odds ratio for influenza in vaccinated versus non-vaccinated persons)]. The VE of the 2010-2011 seasonal influenza vaccine was 49.5% to 45.8% for both influenza A and B, and 50.8% to 47.2% for influenza A, according to the control type. The age-specific adjusted VE was 50.8% to 46.5% among subjects aged 19-49 years and 58.7% to 63.3% among those aged 50-64 years, according to the control type. Statistically significant VE was not found among those aged ≥ 65 years or against influenza B. The 2010-2011 seasonal influenza vaccine was effective for preventing laboratory-confirmed influenza, especially for influenza A, in a Korean population. Evidence of the effectiveness of the influenza vaccine in older adults or against influenza B was not found.
PMID:
23576674
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23576674
Effectiveness of 2010-2011 seasonal influenza vaccine for preventing laboratory-confirmed influenza infection in Korean adult population: Case-control study.
Choi WS, Noh JY, Seo YB, Baek JH, Lee J, Song JY, Park DW, Lee JS, Cheong HJ, Kim WJ.
Source
Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul.
Abstract
We evaluated the effectiveness of the 2010-2011 seasonal influenza vaccine for preventing laboratory-confirmed influenza in a Korean population. A retrospective case-control study was conducted among patients who visited selected hospitals from September 2010 to May 2011. A total of 483 laboratory-confirmed influenza patients were included in the analysis as case subjects. For each case patient, two types of control patients were chosen at a ratio of 1:1:1 and 966 control subjects were selected. Vaccine effectiveness (VE) was defined as [100 ? (1-odds ratio for influenza in vaccinated versus non-vaccinated persons)]. The VE of the 2010-2011 seasonal influenza vaccine was 49.5% to 45.8% for both influenza A and B, and 50.8% to 47.2% for influenza A, according to the control type. The age-specific adjusted VE was 50.8% to 46.5% among subjects aged 19-49 years and 58.7% to 63.3% among those aged 50-64 years, according to the control type. Statistically significant VE was not found among those aged ≥ 65 years or against influenza B. The 2010-2011 seasonal influenza vaccine was effective for preventing laboratory-confirmed influenza, especially for influenza A, in a Korean population. Evidence of the effectiveness of the influenza vaccine in older adults or against influenza B was not found.
PMID:
23576674
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23576674