tetano
Editor, Senior Moderator
J Infect Dis. 2013 Jan 9. [Epub ahead of print]
Effect of the 2009 Influenza A(H1N1) Pandemic on Invasive Pneumococcal Pneumonia.
Fleming-Dutra KE, Taylor T, Link-Gelles R, Garg S, Jhung MA, Finelli L, Jain S, Shay D, Chaves SS, Baumbach J, Hancock EB, Beall B, Bennett N, Zansky S, Petit S, Yousey-Hindes K, Farley MM, Gershman K, Harrison LH, Ryan P, Lexau C, Lynfield R, Reingold A, Schaffner W, Thomas A, Moore MR.
Source
Epidemic Intelligence Service, Centers for Disease Control and Prevention (CDC), Atlanta, GA.
Abstract
Background. Because pneumococcal pneumonia was prevalent during previous influenza pandemics, we evaluated invasive pneumococcal pneumonia (IPP) rates during the 2009 influenza A(H1N1) pandemic.Methods. We identified laboratory-confirmed, influenza-associated hospitalizations and IPP cases (pneumococcus isolated from normally sterile sites with discharge diagnoses of pneumonia) using active, population-based surveillance in the U.S. We compared IPP rates during peak pandemic months (April 2009-March 2010) to mean IPP rates in non-pandemic years (April 2004-March 2009) and, using Poisson models, to 2006-8 influenza seasons.Results. Higher IPP rates occurred during the peak pandemic month compared to non-pandemic periods in 5-24 (IPP rate per 10 million: 48 v. 9 (95% confidence interval (CI) 5-13), 25-49 (74 v. 53 (CI 41-65)), 50-64 (188 v. 114 (CI 85-143)), and ≥65 year-olds (229 v. 187 (CI 159-216)). In the models with seasonal influenza rates included, observed IPP rates during the pandemic peak were within the predicted 95% CIs, suggesting this increase was not greater than observed with seasonal influenza.Conclusions. The recent influenza pandemic likely resulted in an out-of-season IPP peak among persons ≥5 years. The IPP peak's magnitude was similar to that seen during seasonal influenza epidemics.
PMID:
23303809
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23303809
Effect of the 2009 Influenza A(H1N1) Pandemic on Invasive Pneumococcal Pneumonia.
Fleming-Dutra KE, Taylor T, Link-Gelles R, Garg S, Jhung MA, Finelli L, Jain S, Shay D, Chaves SS, Baumbach J, Hancock EB, Beall B, Bennett N, Zansky S, Petit S, Yousey-Hindes K, Farley MM, Gershman K, Harrison LH, Ryan P, Lexau C, Lynfield R, Reingold A, Schaffner W, Thomas A, Moore MR.
Source
Epidemic Intelligence Service, Centers for Disease Control and Prevention (CDC), Atlanta, GA.
Abstract
Background. Because pneumococcal pneumonia was prevalent during previous influenza pandemics, we evaluated invasive pneumococcal pneumonia (IPP) rates during the 2009 influenza A(H1N1) pandemic.Methods. We identified laboratory-confirmed, influenza-associated hospitalizations and IPP cases (pneumococcus isolated from normally sterile sites with discharge diagnoses of pneumonia) using active, population-based surveillance in the U.S. We compared IPP rates during peak pandemic months (April 2009-March 2010) to mean IPP rates in non-pandemic years (April 2004-March 2009) and, using Poisson models, to 2006-8 influenza seasons.Results. Higher IPP rates occurred during the peak pandemic month compared to non-pandemic periods in 5-24 (IPP rate per 10 million: 48 v. 9 (95% confidence interval (CI) 5-13), 25-49 (74 v. 53 (CI 41-65)), 50-64 (188 v. 114 (CI 85-143)), and ≥65 year-olds (229 v. 187 (CI 159-216)). In the models with seasonal influenza rates included, observed IPP rates during the pandemic peak were within the predicted 95% CIs, suggesting this increase was not greater than observed with seasonal influenza.Conclusions. The recent influenza pandemic likely resulted in an out-of-season IPP peak among persons ≥5 years. The IPP peak's magnitude was similar to that seen during seasonal influenza epidemics.
PMID:
23303809
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23303809