tetano
Editor, Senior Moderator
Fundam Clin Pharmacol. 2017 Mar 4. doi: 10.1111/fcp.12281. [Epub ahead of print]
[h=1]Effect of dementia on receipt of influenza vaccine: a cohort study in French older adults using administrative data: 2007-2012.[/h] Gallini A[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Coley N[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Andrieu S[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Lapeyre-Mestre M[SUP]1,[/SUP][SUP]2,[/SUP][SUP]4[/SUP], Gardette V[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Despite guidelines stating the vaccine benefit in this population, older adults with dementia may be less likely to receive influenza vaccine than cognitively intact older adults. But no study has yet reported on vaccine uptake in patients newly diagnosed with dementia or whether years since dementia diagnosis influence vaccine uptake. We conducted a cohort study in the French Health Insurance database (EGB) which contains hospital data and claims for a 1/97[SUP]th[/SUP] random sample of the French population. Diseased subjects were ≥65 years and had a new record of dementia diagnosis between September 1 2007 and August 31 2008. Vaccine receipt was measured via influenza vaccine dispensing in community pharmacies. We described influenza vaccination rates up to 2011-2012 and estimated adjusted relative risks (aRR) for vaccine receipt each year using multivariate modified Poisson models controlling for socio-demographics, comorbidities and health resources use. 407 subjects with dementia (mean age 81.8 years, 69.3% females) and 4862 subjects (mean age 75.2 years, 61.3% females) without dementia were included. In 2008-2009, influenza vaccination prevalence was 70.0% (95%CI=[65.3-74.4]) and 70.2% (95%CI=[68.9-71.4]) in subjects with and without dementia, respectively (aRR=0.93; 95%CI=[0.87-1.00]). In 2009-2010, the aRR was of the same magnitude (aRR=0.96, 95%CI=[0.90-1.03]), but in 2010-2011 and 2011-2012, the aRR was 1.02 (95%CI=[0.94-1.11]) and 1.05 (95%CI=[0.96-1.14]), respectively. Subjects with dementia had a slightly non-significant lower receipt of influenza vaccine in the year following dementia diagnosis than subjects without dementia. In subsequent years, divergent trends were observed in vaccine uptake according to dementia status. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
PMID: 28258589 DOI: 10.1111/fcp.12281
[PubMed - as supplied by publisher]
[h=1]Effect of dementia on receipt of influenza vaccine: a cohort study in French older adults using administrative data: 2007-2012.[/h] Gallini A[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Coley N[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Andrieu S[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Lapeyre-Mestre M[SUP]1,[/SUP][SUP]2,[/SUP][SUP]4[/SUP], Gardette V[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Despite guidelines stating the vaccine benefit in this population, older adults with dementia may be less likely to receive influenza vaccine than cognitively intact older adults. But no study has yet reported on vaccine uptake in patients newly diagnosed with dementia or whether years since dementia diagnosis influence vaccine uptake. We conducted a cohort study in the French Health Insurance database (EGB) which contains hospital data and claims for a 1/97[SUP]th[/SUP] random sample of the French population. Diseased subjects were ≥65 years and had a new record of dementia diagnosis between September 1 2007 and August 31 2008. Vaccine receipt was measured via influenza vaccine dispensing in community pharmacies. We described influenza vaccination rates up to 2011-2012 and estimated adjusted relative risks (aRR) for vaccine receipt each year using multivariate modified Poisson models controlling for socio-demographics, comorbidities and health resources use. 407 subjects with dementia (mean age 81.8 years, 69.3% females) and 4862 subjects (mean age 75.2 years, 61.3% females) without dementia were included. In 2008-2009, influenza vaccination prevalence was 70.0% (95%CI=[65.3-74.4]) and 70.2% (95%CI=[68.9-71.4]) in subjects with and without dementia, respectively (aRR=0.93; 95%CI=[0.87-1.00]). In 2009-2010, the aRR was of the same magnitude (aRR=0.96, 95%CI=[0.90-1.03]), but in 2010-2011 and 2011-2012, the aRR was 1.02 (95%CI=[0.94-1.11]) and 1.05 (95%CI=[0.96-1.14]), respectively. Subjects with dementia had a slightly non-significant lower receipt of influenza vaccine in the year following dementia diagnosis than subjects without dementia. In subsequent years, divergent trends were observed in vaccine uptake according to dementia status. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
PMID: 28258589 DOI: 10.1111/fcp.12281
[PubMed - as supplied by publisher]