tetano
Editor, Senior Moderator
Hum Vaccin Immunother. 2016 Feb 2:0. [Epub ahead of print]
[h=1]Economic Evaluation of Paediatric Influenza Immunisation Programme Compared with Other Paediatric Immunisation Programmes: A Systematic Review.[/h] Gibson E[SUP]1[/SUP], Begum N[SUP]1[/SUP], Sigmundsson B[SUP]1[/SUP], Sackeyfio A[SUP]2[/SUP], Hackett J[SUP]3[/SUP], Rajaram S[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] This study compared the economic value of paediatric immunisation programmes for influenza to those for rotavirus (RV), meningococcal disease (MD), pneumococcal disease (PD), human papillomavirus (HPV), hepatitis B (Hep B), and varicella reported in recent (2000 onwards) cost-effectiveness (CE) studies identified in a systematic review of PubMed, health technology, and vaccination databases. The systematic review yielded 51 economic evaluation studies of paediatric immunisation - 10 (20%) for influenza and 41 (80%) for the other selected diseases. The quality of the eligible articles was assessed using Drummond's checklist. Although inherent challenges and limitations exist when comparing economic evaluations of immunisation programmes, an overall comparison of the included studies demonstrated cost-effectiveness/cost saving for influenza from a European-Union-Five (EU5) and United States (US) perspective; point estimates for cost/quality-adjusted life-years (QALY) from dominance (cost-saving with more effect) to ≤45,444 were reported. The economic value of influenza programmes was comparable to the other vaccines of interest, with cost/QALY in general considerably lower than RV, Hep B, MD and PD. Independent of the perspective and type of analysis, the economic impact of a paediatric influenza immunisation programme was influenced by vaccine efficacy, immunisation coverage, costs, and most significantly by herd immunity. This review suggests that paediatric influenza immunisation may offer a cost effective strategy when compared with HPV and varicella and possibly more value compared with other childhood vaccines (RV, Hep B, MD and PD).
[h=4]KEYWORDS:[/h] Paediatric immunisation programme; cost-effectiveness; economic evaluation; influenza; vaccines
PMID: 26837602 [PubMed - as supplied by publisher]
[h=1]Economic Evaluation of Paediatric Influenza Immunisation Programme Compared with Other Paediatric Immunisation Programmes: A Systematic Review.[/h] Gibson E[SUP]1[/SUP], Begum N[SUP]1[/SUP], Sigmundsson B[SUP]1[/SUP], Sackeyfio A[SUP]2[/SUP], Hackett J[SUP]3[/SUP], Rajaram S[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] This study compared the economic value of paediatric immunisation programmes for influenza to those for rotavirus (RV), meningococcal disease (MD), pneumococcal disease (PD), human papillomavirus (HPV), hepatitis B (Hep B), and varicella reported in recent (2000 onwards) cost-effectiveness (CE) studies identified in a systematic review of PubMed, health technology, and vaccination databases. The systematic review yielded 51 economic evaluation studies of paediatric immunisation - 10 (20%) for influenza and 41 (80%) for the other selected diseases. The quality of the eligible articles was assessed using Drummond's checklist. Although inherent challenges and limitations exist when comparing economic evaluations of immunisation programmes, an overall comparison of the included studies demonstrated cost-effectiveness/cost saving for influenza from a European-Union-Five (EU5) and United States (US) perspective; point estimates for cost/quality-adjusted life-years (QALY) from dominance (cost-saving with more effect) to ≤45,444 were reported. The economic value of influenza programmes was comparable to the other vaccines of interest, with cost/QALY in general considerably lower than RV, Hep B, MD and PD. Independent of the perspective and type of analysis, the economic impact of a paediatric influenza immunisation programme was influenced by vaccine efficacy, immunisation coverage, costs, and most significantly by herd immunity. This review suggests that paediatric influenza immunisation may offer a cost effective strategy when compared with HPV and varicella and possibly more value compared with other childhood vaccines (RV, Hep B, MD and PD).
[h=4]KEYWORDS:[/h] Paediatric immunisation programme; cost-effectiveness; economic evaluation; influenza; vaccines
PMID: 26837602 [PubMed - as supplied by publisher]