Ecology, Evolution and Pathogenesis of Avian Influenza Viruses

[Gert van der Hoek]

Some recent science, published december 22 2006

Ecology, Evolution and Pathogenesis of Avian Influenza Viruses

Munster, V.J.

Doctoral Thesis, Erasmus University Rotterdam

Osterhaus, Prof. Dr. A.D.M.E. (promotor)

https://ep.eur.nl/bitstream/1765/8202/1/061222_Munster,+Vincent+Jacobus.pdf

big file 20694 Kb

https://ep.eur.nl/handle/1765/8202

credits Christian

 

[Laidback Al]

Re: Ecology, Evolution and Pathogenesis of Avian Influenza Viruses

From the concluding chapter

General conclusion
Despite the fact that H5 and H7 subtype influenza A viruses are currently responsible for the outbreaks and epizootics in poultry, it is important to remember that all known pandemics in humans and several problems in poultry had their origin in other subtypes of LPAI viruses. From this historical point of view, the current HPAI H5N1threat is not an isolated problem for public health, animal health and agriculture. A complete inventory of the influenza A viruses detected in wild birds is therefore important. There is a possibility that virtually all influenza A viruses presenting as low or even non-pathogenic in their natural reservoir may have the capacity to become more pathogenic upon transmission to ?non-natural? hosts. The long term and harmonized surveillance in wild birds, poultry and humans in a worldwide multidisciplinary network with a non prestigious exchange of information between the actors, may help assessing the capacity of viruses of subtypes H5 and H7 as well as other subtypes to cross the species barrier and reduce the threats posed to human and animal health.