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ECDC: Communicable Disease Threats Report Week 51, 13–19 December 2025

Commonground

Senior Moderator
This week’s topics

1. Overview of respiratory virus epidemiology in the EU/EEA

2. SARS-CoV-2 variant classification

3. Mpox in the EU/EEA, Western Balkan countries and Türkiye – 2022–2025

4. Leprosy - Romania ex. Indonesia - 2025

5. Mpox clade Ib and clade IIb recombinant strain detected in UK traveller returning from Asia

6. Mpox due to monkeypox virus clades I and II – Global outbreak – 2024–2025

7. Marburg virus disease (MVD) - Ethiopia - 2025

8. Dengue – Multi-country (World) – Monitoring global outbreaks – Monthly update


9. Chikungunya virus disease – Multi-country (World) – Monitoring global outbreaks – Monthly

update


Executive summary

This marks the final weekly CDTR of 2025. Wishing you a joyful holiday season

filled with peace and happiness, and all the best for the year ahead!

Overview of respiratory virus epidemiology in the EU/EEA

• The number of patients presenting to primary care with symptoms of respiratory illness is

elevated in approximately half of the reporting countries. This indicates that there is currently

significant respiratory virus circulation in the European Union/European Economic Area

(EU/EEA).

Influenza virus circulation continues to increase, with most countries now reporting

widespread activity at low-to-medium intensity. Influenza A is dominant in all countries, with

A(H3N2) driving the increasing trend in recent weeks. Circulation is highest in children aged 5–

14 years. Increases in hospitalisation are being observed in some countries, affecting all age

groups, but primarily in adults aged 65 years and above.

European Centre for Disease Prevention and Control, Solna, Sweden

www.ecdc.europa.eu

Classified as ECDC NORMALSURVEILLANCE REPORT
Weekly Communicable Disease Threats Report, Week 51, 13–19 December 2025

• Influenza activity increased three to four weeks earlier than in the previous two seasons.

ECDC’s Threat Assessment Brief assessing the risk of influenza for the EU/EEA in the context of

increasing circulation of A(H3N2) subclade K outlines key recommendations including

vaccination, use of antivirals, use of face masks in healthcare and long-term care facilities, and

healthcare preparedness. These recommendations should be carefully considered and

implemented promptly, given the current epidemiological situation and the approaching festive

period.

Respiratory syncytial virus (RSV)

Continued: https://www.ecdc.europa.eu/sites/de...cable-disease-threats-report-week-51-2025.pdf
 
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