tetano
Editor, Senior Moderator
Curr Opin Virol. 2016 Dec 2;22:22-29. doi: 10.1016/j.coviro.2016.11.006. [Epub ahead of print]
[h=1]Drivers of airborne human-to-human pathogen transmission.[/h] Herfst S[SUP]1[/SUP], B?hringer M[SUP]2[/SUP], Karo B[SUP]3[/SUP], Lawrence P[SUP]4[/SUP], Lewis NS[SUP]5[/SUP], Mina MJ[SUP]6[/SUP], Russell CJ[SUP]7[/SUP], Steel J[SUP]8[/SUP], de Swart RL[SUP]9[/SUP], Menge C[SUP]10[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Airborne pathogens - either transmitted via aerosol or droplets - include a wide variety of highly infectious and dangerous microbes such as variola virus, measles virus, influenza A viruses, Mycobacterium tuberculosis, Streptococcus pneumoniae, and Bordetella pertussis. Emerging zoonotic pathogens, for example, MERS coronavirus, avian influenza viruses, Coxiella, and Francisella, would have pandemic potential were they to acquire efficient human-to-human transmissibility. Here, we synthesize insights from microbiological, medical, social, and economic sciences to provide known mechanisms of aerosolized transmissibility and identify knowledge gaps that limit emergency preparedness plans. In particular, we propose a framework of drivers facilitating human-to-human transmission with the airspace between individuals as an intermediate stage. The model is expected to enhance identification and risk assessment of novel pathogens.
Copyright © 2016 The Author(s). Published by Elsevier B.V. All rights reserved.
PMID: 27918958 DOI: 10.1016/j.coviro.2016.11.006
[PubMed - as supplied by publisher]
[h=1]Drivers of airborne human-to-human pathogen transmission.[/h] Herfst S[SUP]1[/SUP], B?hringer M[SUP]2[/SUP], Karo B[SUP]3[/SUP], Lawrence P[SUP]4[/SUP], Lewis NS[SUP]5[/SUP], Mina MJ[SUP]6[/SUP], Russell CJ[SUP]7[/SUP], Steel J[SUP]8[/SUP], de Swart RL[SUP]9[/SUP], Menge C[SUP]10[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Airborne pathogens - either transmitted via aerosol or droplets - include a wide variety of highly infectious and dangerous microbes such as variola virus, measles virus, influenza A viruses, Mycobacterium tuberculosis, Streptococcus pneumoniae, and Bordetella pertussis. Emerging zoonotic pathogens, for example, MERS coronavirus, avian influenza viruses, Coxiella, and Francisella, would have pandemic potential were they to acquire efficient human-to-human transmissibility. Here, we synthesize insights from microbiological, medical, social, and economic sciences to provide known mechanisms of aerosolized transmissibility and identify knowledge gaps that limit emergency preparedness plans. In particular, we propose a framework of drivers facilitating human-to-human transmission with the airspace between individuals as an intermediate stage. The model is expected to enhance identification and risk assessment of novel pathogens.
Copyright © 2016 The Author(s). Published by Elsevier B.V. All rights reserved.
PMID: 27918958 DOI: 10.1016/j.coviro.2016.11.006
[PubMed - as supplied by publisher]