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Source: http://www.nature.com/news/distinctive-virus-behind-mystery-horse-disease-1.12624
Distinctive virus behind mystery horse disease
Origin of Theiler hepatitis was a century-old puzzle.
Ed Yong
18 March 2013
A mysterious hepatitis that causes liver failure in most horses has now been linked to an unusual virus.
For almost 100 years, veterinarians have puzzled over the cause of Theiler disease, a mysterious type of equine hepatitis that is linked to blood products and causes liver failure in up to 90% of afflicted animals.
A team of US scientists has now discovered that the disease is caused by a virus that shares just 35% of its amino acid sequences with its closest-known relative. The team named it Theiler disease-associated virus (TDAV), and published the discovery in the Proceedings of the National Academy of Sciences Nature
doi:10.1038/nature.2013.12624
References
Chandriani, S. et al. Proc. Natl Acad. Sci. USA http://dx.doi.org/10.1073/pnas.1219217110 (2013)....
...
Distinctive virus behind mystery horse disease
Origin of Theiler hepatitis was a century-old puzzle.
Ed Yong
18 March 2013
A mysterious hepatitis that causes liver failure in most horses has now been linked to an unusual virus.
For almost 100 years, veterinarians have puzzled over the cause of Theiler disease, a mysterious type of equine hepatitis that is linked to blood products and causes liver failure in up to 90% of afflicted animals.
A team of US scientists has now discovered that the disease is caused by a virus that shares just 35% of its amino acid sequences with its closest-known relative. The team named it Theiler disease-associated virus (TDAV), and published the discovery in the Proceedings of the National Academy of Sciences Nature
doi:10.1038/nature.2013.12624
References
Chandriani, S. et al. Proc. Natl Acad. Sci. USA http://dx.doi.org/10.1073/pnas.1219217110 (2013)....
...