tetano
Editor, Senior Moderator
Diseases
. 2022 Aug 19;10(3):53.
doi: 10.3390/diseases10030053.
Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality
Venice Chávez-Valencia[SUP] 1 [/SUP], Citlalli Orizaga-de-la-Cruz[SUP] 1 [/SUP], Francisco Alejandro Lagunas-Rangel[SUP] 2 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) is a disease caused by infection with the SARS-CoV-2 virus and has represented one of the greatest challenges humanity has faced in recent years. The virus can infect a large number of organs, including the lungs and upper respiratory tract, brain, liver, kidneys, and intestines, among many others. Although the greatest damage occurs in the lungs, the kidneys are not exempt, and acute kidney injury (AKI) can occur in patients with COVID-19. Indeed, AKI is one of the most frequent and serious organic complications of COVID-19. The incidence of COVID-19 AKI varies widely, and the exact mechanisms of how the virus damages the kidney are still unknown. For this reason, the purpose of this review was to assess current findings on the pathogenesis, clinical features, therapy, and mortality of COVID-19 AKI.
Keywords: ACE2; AKI; SARS-CoV-2; molecular mechanisms.
. 2022 Aug 19;10(3):53.
doi: 10.3390/diseases10030053.
Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality
Venice Chávez-Valencia[SUP] 1 [/SUP], Citlalli Orizaga-de-la-Cruz[SUP] 1 [/SUP], Francisco Alejandro Lagunas-Rangel[SUP] 2 [/SUP]
Affiliations
- PMID: 35997358
- DOI: 10.3390/diseases10030053
Abstract
Coronavirus disease 2019 (COVID-19) is a disease caused by infection with the SARS-CoV-2 virus and has represented one of the greatest challenges humanity has faced in recent years. The virus can infect a large number of organs, including the lungs and upper respiratory tract, brain, liver, kidneys, and intestines, among many others. Although the greatest damage occurs in the lungs, the kidneys are not exempt, and acute kidney injury (AKI) can occur in patients with COVID-19. Indeed, AKI is one of the most frequent and serious organic complications of COVID-19. The incidence of COVID-19 AKI varies widely, and the exact mechanisms of how the virus damages the kidney are still unknown. For this reason, the purpose of this review was to assess current findings on the pathogenesis, clinical features, therapy, and mortality of COVID-19 AKI.
Keywords: ACE2; AKI; SARS-CoV-2; molecular mechanisms.