Discussion - monkeypox treatments?

[DavidH]

Can't find a MonkeyPox specific thread (someone probably should start one), but have some questions / findings:

A few things:

1. Appears that Ph-Dependency as a treatment issue may not be viable. I think I am seeing that it may have dual entry (1 is ph-dependent; 1 is ph-independent) so they sort of cancel out that aspect. Although I thought I saw a study that referenced Chloroquine as being semi-succesful, but can't find the study again. That mght indcate some ph-dependency treatment benefit. Any help?
2. Only thing I found so far that appeared to be a succesful approach was Resveratrol. Here is a quote,
   
   "Resveratrol also significantly reduced the replication of monkeypox virus, a zoonotic virus that is endemic in Western and Central Africa and causes human mortality."
   
   Came from following study: https://www.frontiersin.org/articles/10.3389/fmicb.2017.02196/full
3. Anybody seeing any promising aspects of treatment mechanisms? In studies? Any trends? Saw stories that susggested it being sexually transmissable, but the following research was very interesting, both from an infection timeline, and possible aerosol spread vector. LINK: https://www.researchgate.net/public...ues_Infected_with_Aerosolized_Monkeypox_Virus

If there is a main MonkeyPox thread I missed, I am game that thiis be moved there.

 

[sharon sanders]

This is a very serious disease. If you suspect that you might have monkeypox - do not attempt to treat yourself. Immediately seek medical attention.

If you have any medical questions, please consult your medical practitioner. Do not take medical advice from the internet.


From a CDC information page:


"Treatment


Currently, there is no proven, safe treatment for monkeypox virus infection. For purposes of controlling a monkeypox outbreak in the United States, smallpox vaccine, antivirals, and vaccinia immune globulin (VIG) can be used. Learn more about smallpox vaccine, antivirals, and VIG treatments."


https://www.cdc.gov/poxvirus/monkeypox/treatment.html

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From the Cleveland Clinic:

snip

"Is monkeypox fatal?


Monkeypox is milder than smallpox, but it can still be fatal. Monkeypox causes death in up to 10% of cases.

snip

Early symptoms are flu-like and include fever, chills and body aches. After a few days, a rash will begin to develop. Monkeypox is milder than smallpox, but it’s still important to be seen by a healthcare provider if you develop any symptoms."


https://my.clevelandclinic.org/healt...2371-monkeypox

 

[alert]

Yup, my instinct on home treatment of monkeypox is the same as mine was in 2014 when home treatment of Ebola was being considered. Just don't do it. The result is that you will not do anything to improve your health and will likely infect others in the process of attempting home treatment. I forget the wording we used in 2014, but it was something like that if you try home treatment, you will die and everyone around you will too. Obviously, this is a little milder than Ebola, but the basic principle stands.

If this virus goes pandemic and the health care system breaks down entirely, that's a different situation. But let's hope we don't cross that bridge.