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Volume 17, Number 9?September 2011
Research
Differential Effects of Pandemic (H1N1) 2009 on Remote and Indigenous Groups, Northern Territory, Australia, 2009
James McCracken Trauer, Comments to Author Karen Louise Laurie, Joseph McDonnell, Anne Kelso, and Peter Gregory Markey
Author affiliations: Centre for Disease Control, Tiwi, Northern Territory, Australia (J.M. Trauer, P.G. Markey); World Health Organization Collaborating Centre for Reference and Research in Influenza, North Melbourne, Victoria, Australia (K.L. Laurie, A. Kelso); and Menzies School of Health Research, Tiwi (J. McDonnell)
Suggested citation for this article
Abstract
Pandemic (H1N1) 2009 influenza spread through the Northern Territory, Australia, during June?August 2009. We performed 2 cross-sectional serologic surveys on specimens from Northern Territory residents, with 445 specimens obtained prepandemic and 1,689 specimens postpandemic. Antibody titers were determined by hemagglutination inhibition against reference virus A/California/7/2009 on serum samples collected opportunistically from outpatients. All specimens had data for patients' gender, age, and address, with patients' indigenous status determined for 94.1%. Protective immunity (titer >40) was present in 7.6% (95% confidence interval [CI] 5.2%?10.1%) of prepandemic specimens and 19.5% (95% CI 17.6%?21.4%) of postpandemic specimens, giving a population-standardized attack rate of 14.9% (95% CI 11.0%?18.9%). Prepandemic proportion of immune persons was greater with increasing age but did not differ by other demographic characteristics. Postpandemic proportion of immune persons was greater in younger groups and around double in indigenous persons. Postpandemic proportion immune was geographically heterogeneous, particularly among remote-living and indigenous groups.
http://www.cdc.gov/eid/content/17/9/101196.htm
Volume 17, Number 9?September 2011
Research
Differential Effects of Pandemic (H1N1) 2009 on Remote and Indigenous Groups, Northern Territory, Australia, 2009
James McCracken Trauer, Comments to Author Karen Louise Laurie, Joseph McDonnell, Anne Kelso, and Peter Gregory Markey
Author affiliations: Centre for Disease Control, Tiwi, Northern Territory, Australia (J.M. Trauer, P.G. Markey); World Health Organization Collaborating Centre for Reference and Research in Influenza, North Melbourne, Victoria, Australia (K.L. Laurie, A. Kelso); and Menzies School of Health Research, Tiwi (J. McDonnell)
Suggested citation for this article
Abstract
Pandemic (H1N1) 2009 influenza spread through the Northern Territory, Australia, during June?August 2009. We performed 2 cross-sectional serologic surveys on specimens from Northern Territory residents, with 445 specimens obtained prepandemic and 1,689 specimens postpandemic. Antibody titers were determined by hemagglutination inhibition against reference virus A/California/7/2009 on serum samples collected opportunistically from outpatients. All specimens had data for patients' gender, age, and address, with patients' indigenous status determined for 94.1%. Protective immunity (titer >40) was present in 7.6% (95% confidence interval [CI] 5.2%?10.1%) of prepandemic specimens and 19.5% (95% CI 17.6%?21.4%) of postpandemic specimens, giving a population-standardized attack rate of 14.9% (95% CI 11.0%?18.9%). Prepandemic proportion of immune persons was greater with increasing age but did not differ by other demographic characteristics. Postpandemic proportion of immune persons was greater in younger groups and around double in indigenous persons. Postpandemic proportion immune was geographically heterogeneous, particularly among remote-living and indigenous groups.
http://www.cdc.gov/eid/content/17/9/101196.htm