tetano
Editor, Senior Moderator
Obstet Gynecol. 2010 Feb;115(2 Pt 2):409-12.
Diagnostic dilemmas in a pregnant woman with influenza A (H1N1) infection.
Greer LG, Abbassi-Ghanavati M, Sheffield JS, Casey BM.
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Parkland Health and Hospital System, Dallas, Texas 75390-9032, USA. laura.greer@utsouthwestern.edu
Abstract
BACKGROUND: Pregnant women are at increased risk for complications from seasonal influenza. Early data suggest that influenza A (H1N1) may present an even greater risk. CASE: We present the case of a pregnant woman with severe pulmonary complications from 2009 H1N1 whose care was further complicated by delay in diagnosis and unusual laboratory abnormalities. CONCLUSION: H1N1 may pose several diagnostic challenges for obstetricians, including increased rates of serious pulmonary complications, decreased sensitivity of rapid tests with delay in initiation of antiviral therapy, and abnormal laboratory findings usually associated with other complications of pregnancy. We document these problems, urge initiation of antiviral therapy based on clinical suspicion, and recognize the potential laboratory abnormalities that may be associated with severe influenza illness.
PMID: 20093861 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/20093861
Diagnostic dilemmas in a pregnant woman with influenza A (H1N1) infection.
Greer LG, Abbassi-Ghanavati M, Sheffield JS, Casey BM.
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Parkland Health and Hospital System, Dallas, Texas 75390-9032, USA. laura.greer@utsouthwestern.edu
Abstract
BACKGROUND: Pregnant women are at increased risk for complications from seasonal influenza. Early data suggest that influenza A (H1N1) may present an even greater risk. CASE: We present the case of a pregnant woman with severe pulmonary complications from 2009 H1N1 whose care was further complicated by delay in diagnosis and unusual laboratory abnormalities. CONCLUSION: H1N1 may pose several diagnostic challenges for obstetricians, including increased rates of serious pulmonary complications, decreased sensitivity of rapid tests with delay in initiation of antiviral therapy, and abnormal laboratory findings usually associated with other complications of pregnancy. We document these problems, urge initiation of antiviral therapy based on clinical suspicion, and recognize the potential laboratory abnormalities that may be associated with severe influenza illness.
PMID: 20093861 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/20093861