tetano
Editor, Senior Moderator
Diabetes Res Clin Pract
. 2020 May 21;108228.
doi: 10.1016/j.diabres.2020.108228. Online ahead of print.
SARS-CoV-2 and Diabetes: New Challenges for the Disease
Cec?lia Cristelo[SUP] 1 [/SUP], Cl?udia Azevedo[SUP] 1 [/SUP], Joana Moreira Marques[SUP] 2 [/SUP], Rute Nunes[SUP] 3 [/SUP], Bruno Sarmento[SUP] 4 [/SUP]
Affiliations
Abstract
A novel small enveloped RNA virus with the typical characteristic of the family to which it belongs, a crown, hence the name coronavirus, appeared in December 2019 in Wuhan, China, and subdued the world to its influence. The particular severity of the disease and higher mortality rates in patients with associated morbidities, including hypertension, obesity and diabetes, increases the concern over the consequences of this pandemic. In this review, the features of SARS-CoV-2 will be addressed, as well as the reasons why it poses a particular challenge to diabetic patients. We will also highlight the recent treatment strategies being explored to control this pandemic. Emerging evidence demonstrates that the correct management of diabetes in those patients infected with SARS-CoV-2 is of utmost importance for the viral disease progression, therefore, the importance of blood glucose control will also be addressed.
Keywords: ACE inhibitors; ACE-2; COVID-19; SARS-CoV-2; diabetes; glycemic control.
. 2020 May 21;108228.
doi: 10.1016/j.diabres.2020.108228. Online ahead of print.
SARS-CoV-2 and Diabetes: New Challenges for the Disease
Cec?lia Cristelo[SUP] 1 [/SUP], Cl?udia Azevedo[SUP] 1 [/SUP], Joana Moreira Marques[SUP] 2 [/SUP], Rute Nunes[SUP] 3 [/SUP], Bruno Sarmento[SUP] 4 [/SUP]
Affiliations
- PMID: 32446801
- DOI: 10.1016/j.diabres.2020.108228
Abstract
A novel small enveloped RNA virus with the typical characteristic of the family to which it belongs, a crown, hence the name coronavirus, appeared in December 2019 in Wuhan, China, and subdued the world to its influence. The particular severity of the disease and higher mortality rates in patients with associated morbidities, including hypertension, obesity and diabetes, increases the concern over the consequences of this pandemic. In this review, the features of SARS-CoV-2 will be addressed, as well as the reasons why it poses a particular challenge to diabetic patients. We will also highlight the recent treatment strategies being explored to control this pandemic. Emerging evidence demonstrates that the correct management of diabetes in those patients infected with SARS-CoV-2 is of utmost importance for the viral disease progression, therefore, the importance of blood glucose control will also be addressed.
Keywords: ACE inhibitors; ACE-2; COVID-19; SARS-CoV-2; diabetes; glycemic control.