tetano
Editor, Senior Moderator
Diabetes Res Clin Pract
. 2020 Jul 11;108300.
doi: 10.1016/j.diabres.2020.108300. Online ahead of print.
A case presentation for positive SARS-CoV-2 RNA recurrence in a patient with a history of type 2 diabetes that had recovered from severe COVID-19
Chengyun Dou[SUP] 1 [/SUP], Xia Xie[SUP] 1 [/SUP], Zhongtian Peng[SUP] 1 [/SUP], Haibo Tang[SUP] 1 [/SUP], Zheng Jiang[SUP] 2 [/SUP], Zhefeng Zhong[SUP] 3 [/SUP], Jian Tang[SUP] 4 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) is considered to be spread primarily by people who have tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we discuss a patient with severe COVID-19 and a history of type 2 diabetes who had a recurrence of positive SARS-CoV-2 ribonucleic acid (RNA) after recovering. The patient was initially discharged after two consecutive negative SARS-CoV-2 RNA tests and partially absorbed bilateral lesions on chest computed tomography (CT). However, at his first follow-up, reverse transcription-polymerase chain reaction (RT-PCR) assay with an oropharyngeal swab sample was positive for SARS-CoV-2. Despite this, he displayed no obvious clinical symptoms and improved chest CT. The patient was prescribed anti-viral medication. Eight consecutive RT-PCR assays on oropharyngeal swab specimens were conducted after he was re-admitted to our hospital. The results tested positive on the 12[SUP]th[/SUP], 14[SUP]th[/SUP], 19[SUP]th[/SUP], 23[SUP]rd[/SUP] and 26[SUP]th[/SUP] of March and negative on the 28[SUP]th[/SUP] of March, and 6[SUP]th[/SUP] and 12[SUP]th[/SUP] of April. After his second discharge, he has tested negative for 5 weeks. This case highlights the importance of active surveillance of SARS-CoV-2 RNA during the follow-up period so that an infectivity assessment can be made.
Keywords: Coronavirus disease 2019; Recurrence; SARS-CoV-2; Severe; Type 2 diabetes.
. 2020 Jul 11;108300.
doi: 10.1016/j.diabres.2020.108300. Online ahead of print.
A case presentation for positive SARS-CoV-2 RNA recurrence in a patient with a history of type 2 diabetes that had recovered from severe COVID-19
Chengyun Dou[SUP] 1 [/SUP], Xia Xie[SUP] 1 [/SUP], Zhongtian Peng[SUP] 1 [/SUP], Haibo Tang[SUP] 1 [/SUP], Zheng Jiang[SUP] 2 [/SUP], Zhefeng Zhong[SUP] 3 [/SUP], Jian Tang[SUP] 4 [/SUP]
Affiliations
- PMID: 32663490
- DOI: 10.1016/j.diabres.2020.108300
Abstract
Coronavirus disease 2019 (COVID-19) is considered to be spread primarily by people who have tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we discuss a patient with severe COVID-19 and a history of type 2 diabetes who had a recurrence of positive SARS-CoV-2 ribonucleic acid (RNA) after recovering. The patient was initially discharged after two consecutive negative SARS-CoV-2 RNA tests and partially absorbed bilateral lesions on chest computed tomography (CT). However, at his first follow-up, reverse transcription-polymerase chain reaction (RT-PCR) assay with an oropharyngeal swab sample was positive for SARS-CoV-2. Despite this, he displayed no obvious clinical symptoms and improved chest CT. The patient was prescribed anti-viral medication. Eight consecutive RT-PCR assays on oropharyngeal swab specimens were conducted after he was re-admitted to our hospital. The results tested positive on the 12[SUP]th[/SUP], 14[SUP]th[/SUP], 19[SUP]th[/SUP], 23[SUP]rd[/SUP] and 26[SUP]th[/SUP] of March and negative on the 28[SUP]th[/SUP] of March, and 6[SUP]th[/SUP] and 12[SUP]th[/SUP] of April. After his second discharge, he has tested negative for 5 weeks. This case highlights the importance of active surveillance of SARS-CoV-2 RNA during the follow-up period so that an infectivity assessment can be made.
Keywords: Coronavirus disease 2019; Recurrence; SARS-CoV-2; Severe; Type 2 diabetes.