tetano
Editor, Senior Moderator
BMC Pregnancy Childbirth. 2019 Dec 19;19(1):510. doi: 10.1186/s12884-019-2628-5. [h=1]Determinants of influenza vaccination uptake in pregnancy: a large single-Centre cohort study.[/h]
Bartolo S[SUP]1,[/SUP][SUP]2[/SUP], Deliege E[SUP]3[/SUP], Mancel O[SUP]3[/SUP], Dufour P[SUP]3[/SUP], Vanderstichele S[SUP]3[/SUP], Roumilhac M[SUP]3[/SUP], Hammou Y[SUP]3[/SUP], Carpentier S[SUP]3[/SUP], Dessein R[SUP]4[/SUP], Subtil D[SUP]5,[/SUP][SUP]3[/SUP], Faure K[SUP]4,[/SUP][SUP]6[/SUP].
[h=3]Author information[/h] 1 University Lille, EA 2694 : ?pid?miologie et qualit? des soins, p?le recherche aile Est 2?me ?tage, 59 045 cedex, 1 Place de Verdun, 59 000, Lille, France. stephanie.bartolo@gmail.com. 2 Douai hospital, route de Cambrai, -, 10740 - 59507, Douai Cedex, BP, France. stephanie.bartolo@gmail.com. 3 University Lille, CHU Lille, P?le Femme M?re Nouveau-n?, Avenue Eug?ne Avin?e, 59000, Lille, France. 4 University Lille, EA7366, Recherche Translationelle Relation H?te-Pathog?nes, Facult? de M?decine P?le Recherche 5 ?me ?tage Ouest, 1 Place de Verdun, 59045, Lille, France. 5 University Lille, EA 2694 : ?pid?miologie et qualit? des soins, p?le recherche aile Est 2?me ?tage, 59 045 cedex, 1 Place de Verdun, 59 000, Lille, France. 6 University Lille, CHU Lille, Service de Maladies Infectieuses, rue Michel Polonowski, 59000, Lille, France.
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Although vaccination of pregnant women against influenza is recommended, the vaccination rate remains low. We conducted a study to identify determinants of influenza vaccination uptake in pregnancy in order to identify strategies to improve seasonal influenza vaccination rates.
[h=4]METHODS:[/h] Prospective observational hospital-based study in the French hospital performing the highest number of deliveries, located in the city of Lille, among all women who had given birth during the 2014-2015 influenza season. Data were collected through a self-completed questionnaire and from medical files. The vaccination uptake was self-reported. Determinants of vaccination uptake were identified using logistic regression analysis.
[h=4]RESULTS:[/h] Of the 2045 women included in the study, 35.5% reported that they had been vaccinated against influenza during their pregnancy. The principal factors significantly associated with greater vaccination uptake were previous influenza vaccination (50.9% vs 20.2%, OR 4.1, 95% CI 3.1-5.5), nulliparity (41.0% vs 31.3%, OR 2.5, 95% CI 1.7-3.7), history of preterm delivery < 34 weeks (43.4% vs 30.3%, OR 2.3, 95% CI 1.1-4.9), the mother's perception that the frequency of vaccine complications for babies is very low (54.6% vs 20.6%, OR 1.1, 95% CI 0.5-2.2), the mother's good knowledge of influenza and its vaccine (61.7% vs 24.4%, OR 3.1, 95% CI 2.2-4.4), hospital-based prenatal care in their first trimester of pregnancy (55.0% vs 30.2%, OR 2.1, 95% CI 1.2-3.7), vaccination recommendations during pregnancy by a healthcare worker (47.0% vs 2.7%, OR 18.8, 95% CI 10.0-35.8), receipt of a vaccine reimbursement form (52.4% vs 18.6%, OR 2.0, 95% CI 1.5-2.7), and information from at least one healthcare worker about the vaccine (43.8% vs 19.1%, OR 1.8, 95% CI 1.3-2.6).
[h=4]CONCLUSIONS:[/h] Our findings suggest that in order to increase flu vaccination compliance among pregnant women, future public health programmes must ensure cost-free access to vaccination, and incorporate education about the risks of influenza and the efficacy/safety of vaccination and clear recommendations from healthcare professionals into routine antenatal care.
[h=4]KEYWORDS:[/h] Behaviours; Health knowledge; Influenza vaccine; Pregnancy
PMID: 31856752 DOI: 10.1186/s12884-019-2628-5
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Bartolo S[SUP]1,[/SUP][SUP]2[/SUP], Deliege E[SUP]3[/SUP], Mancel O[SUP]3[/SUP], Dufour P[SUP]3[/SUP], Vanderstichele S[SUP]3[/SUP], Roumilhac M[SUP]3[/SUP], Hammou Y[SUP]3[/SUP], Carpentier S[SUP]3[/SUP], Dessein R[SUP]4[/SUP], Subtil D[SUP]5,[/SUP][SUP]3[/SUP], Faure K[SUP]4,[/SUP][SUP]6[/SUP].
[h=3]Author information[/h] 1 University Lille, EA 2694 : ?pid?miologie et qualit? des soins, p?le recherche aile Est 2?me ?tage, 59 045 cedex, 1 Place de Verdun, 59 000, Lille, France. stephanie.bartolo@gmail.com. 2 Douai hospital, route de Cambrai, -, 10740 - 59507, Douai Cedex, BP, France. stephanie.bartolo@gmail.com. 3 University Lille, CHU Lille, P?le Femme M?re Nouveau-n?, Avenue Eug?ne Avin?e, 59000, Lille, France. 4 University Lille, EA7366, Recherche Translationelle Relation H?te-Pathog?nes, Facult? de M?decine P?le Recherche 5 ?me ?tage Ouest, 1 Place de Verdun, 59045, Lille, France. 5 University Lille, EA 2694 : ?pid?miologie et qualit? des soins, p?le recherche aile Est 2?me ?tage, 59 045 cedex, 1 Place de Verdun, 59 000, Lille, France. 6 University Lille, CHU Lille, Service de Maladies Infectieuses, rue Michel Polonowski, 59000, Lille, France.
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Although vaccination of pregnant women against influenza is recommended, the vaccination rate remains low. We conducted a study to identify determinants of influenza vaccination uptake in pregnancy in order to identify strategies to improve seasonal influenza vaccination rates.
[h=4]METHODS:[/h] Prospective observational hospital-based study in the French hospital performing the highest number of deliveries, located in the city of Lille, among all women who had given birth during the 2014-2015 influenza season. Data were collected through a self-completed questionnaire and from medical files. The vaccination uptake was self-reported. Determinants of vaccination uptake were identified using logistic regression analysis.
[h=4]RESULTS:[/h] Of the 2045 women included in the study, 35.5% reported that they had been vaccinated against influenza during their pregnancy. The principal factors significantly associated with greater vaccination uptake were previous influenza vaccination (50.9% vs 20.2%, OR 4.1, 95% CI 3.1-5.5), nulliparity (41.0% vs 31.3%, OR 2.5, 95% CI 1.7-3.7), history of preterm delivery < 34 weeks (43.4% vs 30.3%, OR 2.3, 95% CI 1.1-4.9), the mother's perception that the frequency of vaccine complications for babies is very low (54.6% vs 20.6%, OR 1.1, 95% CI 0.5-2.2), the mother's good knowledge of influenza and its vaccine (61.7% vs 24.4%, OR 3.1, 95% CI 2.2-4.4), hospital-based prenatal care in their first trimester of pregnancy (55.0% vs 30.2%, OR 2.1, 95% CI 1.2-3.7), vaccination recommendations during pregnancy by a healthcare worker (47.0% vs 2.7%, OR 18.8, 95% CI 10.0-35.8), receipt of a vaccine reimbursement form (52.4% vs 18.6%, OR 2.0, 95% CI 1.5-2.7), and information from at least one healthcare worker about the vaccine (43.8% vs 19.1%, OR 1.8, 95% CI 1.3-2.6).
[h=4]CONCLUSIONS:[/h] Our findings suggest that in order to increase flu vaccination compliance among pregnant women, future public health programmes must ensure cost-free access to vaccination, and incorporate education about the risks of influenza and the efficacy/safety of vaccination and clear recommendations from healthcare professionals into routine antenatal care.
[h=4]KEYWORDS:[/h] Behaviours; Health knowledge; Influenza vaccine; Pregnancy
PMID: 31856752 DOI: 10.1186/s12884-019-2628-5
Free full text