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Detection of a transient R292K mutation in Influenza A/H3N2 viruses shed for several weeks by an immunocompromised patient

tetano

Editor, Senior Moderator
J Clin Microbiol. 2015 Jan 14. pii: JCM.02845-14. [Epub ahead of print]
[h=1]Detection of a transient R292K mutation in Influenza A/H3N2 viruses shed for several weeks by an immunocompromised patient.[/h] Babady NE[SUP]1[/SUP], Laplante JM[SUP]2[/SUP], Tang YW[SUP]3[/SUP], St George K[SUP]2[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] We describe the case of an immunocompromised patient, positive for influenza A virus (H3N2), in whom the neuraminidase R292K mutation was transiently detected during oseltamivir treatment. The R292K mutation was identified by direct testing in three of eleven respiratory specimens collected throughout the patient's illness, but in none of the cultures from those specimens.
Copyright ? 2015, American Society for Microbiology. All Rights Reserved.


PMID: 25588658 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25588658
 
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