tetano
Editor, Senior Moderator
Open Forum Infect Dis. 2019 Nov 18;6(12)
fz493. doi: 10.1093/ofid/ofz493. eCollection 2019 Dec. [h=1]Detection and Characterization of Influenza B Virus With Reduced Neuraminidase Susceptibility in a Stem Cell Transplant Recipient.[/h]
Kodiyanplakkal RPL[SUP]1[/SUP], Laplante JM[SUP]2[/SUP], Westblade LF[SUP]1,[/SUP][SUP]3[/SUP], van Besien K[SUP]4[/SUP], Salvatore M[SUP]5[/SUP], St George K[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Antiviral-resistant influenza viruses in the clinical environment, especially type B, are reported rarely. A stem cell transplant recipient remained influenza B positive for 2 months, despite repeated antiviral treatments. Laboratory tests demonstrated the evolution and persistence of neuraminidase inhibitor-resistant influenza B virus with a substitution at codon 119.
? The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
[h=4]KEYWORDS:[/h] antiviral resistance; influenza B virus; neuraminidase inhibitors; neuraminidase mutation; stem cell transplant
PMID: 32128335 PMCID: PMC7047943 DOI: 10.1093/ofid/ofz493
Free PMC Article
fz493. doi: 10.1093/ofid/ofz493. eCollection 2019 Dec. [h=1]Detection and Characterization of Influenza B Virus With Reduced Neuraminidase Susceptibility in a Stem Cell Transplant Recipient.[/h] Kodiyanplakkal RPL[SUP]1[/SUP], Laplante JM[SUP]2[/SUP], Westblade LF[SUP]1,[/SUP][SUP]3[/SUP], van Besien K[SUP]4[/SUP], Salvatore M[SUP]5[/SUP], St George K[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Antiviral-resistant influenza viruses in the clinical environment, especially type B, are reported rarely. A stem cell transplant recipient remained influenza B positive for 2 months, despite repeated antiviral treatments. Laboratory tests demonstrated the evolution and persistence of neuraminidase inhibitor-resistant influenza B virus with a substitution at codon 119.
? The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
[h=4]KEYWORDS:[/h] antiviral resistance; influenza B virus; neuraminidase inhibitors; neuraminidase mutation; stem cell transplant
PMID: 32128335 PMCID: PMC7047943 DOI: 10.1093/ofid/ofz493
Free PMC Article