tetano
Editor, Senior Moderator
J Med Virol. 2016 Dec 12. doi: 10.1002/jmv.24753. [Epub ahead of print]
[h=1]Detecting and quantifying influenza virus with self- versus investigator-collected mid-turbinate nasal swabs.[/h] Granados A[SUP]1,[/SUP][SUP]2[/SUP], Quach S[SUP]1[/SUP], McGeer A[SUP]2,[/SUP][SUP]3,[/SUP][SUP]4[/SUP], Gubbay JB[SUP]1,[/SUP][SUP]2,[/SUP][SUP]5[/SUP], Kwong JC[SUP]1,[/SUP][SUP]6,[/SUP][SUP]7,[/SUP][SUP]8,[/SUP][SUP]9[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] We compared pairs of self- and investigator-collected mid-turbinate nasal swabs to detect and quantify influenza viral loads. We used RNase P, which reflects presence of human cells to determine adequate sample collection. Sixteen pairs of influenza-positive swabs and 25 pairs of influenza-negative swabs were included in this study. The median influenza A viral loads for self- and investigator-collected swabs were 1.68 and 1.67 log[SUB]10[/SUB] copies/ml, respectively (p = 0.96). RNase P loads were also similar between self- and investigator-collected swabs (p = 0.51). Self-collected mid-turbinate nasal swabs yield comparable viral loads to investigator-collected swabs, and therefore might be considered for research and clinical management. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Influenza A; qPCR; self-collected nasal swab
PMID: 27943313 DOI: 10.1002/jmv.24753
[PubMed - as supplied by publisher]
[h=1]Detecting and quantifying influenza virus with self- versus investigator-collected mid-turbinate nasal swabs.[/h] Granados A[SUP]1,[/SUP][SUP]2[/SUP], Quach S[SUP]1[/SUP], McGeer A[SUP]2,[/SUP][SUP]3,[/SUP][SUP]4[/SUP], Gubbay JB[SUP]1,[/SUP][SUP]2,[/SUP][SUP]5[/SUP], Kwong JC[SUP]1,[/SUP][SUP]6,[/SUP][SUP]7,[/SUP][SUP]8,[/SUP][SUP]9[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] We compared pairs of self- and investigator-collected mid-turbinate nasal swabs to detect and quantify influenza viral loads. We used RNase P, which reflects presence of human cells to determine adequate sample collection. Sixteen pairs of influenza-positive swabs and 25 pairs of influenza-negative swabs were included in this study. The median influenza A viral loads for self- and investigator-collected swabs were 1.68 and 1.67 log[SUB]10[/SUB] copies/ml, respectively (p = 0.96). RNase P loads were also similar between self- and investigator-collected swabs (p = 0.51). Self-collected mid-turbinate nasal swabs yield comparable viral loads to investigator-collected swabs, and therefore might be considered for research and clinical management. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Influenza A; qPCR; self-collected nasal swab
PMID: 27943313 DOI: 10.1002/jmv.24753
[PubMed - as supplied by publisher]