tetano
Editor, Senior Moderator
Dermatol Ther. 2020 May 10. doi: 10.1111/dth.13549. [Epub ahead of print]
Cutaneous Signs in COVID-19 Patients: A Review.
Wollina U[SUP]1[/SUP], Karadağ AS[SUP]2[/SUP], Rowland-Payne C[SUP]3[/SUP], Chiriac A[SUP]4,[/SUP][SUP]5,[/SUP][SUP]6[/SUP], Lotti T[SUP]7[/SUP].
Author information
Abstract
COVID-19 pandemic caused by beta-coronavirus SARS-CoV-2 primarily affects the epithelium of the airways. With the increasing involvement of dermatologist in management of this crisis, cutaneous symptoms gained more and more attention. In this review we will describe cutaneous symptoms of patients of all ages in association with COVID-19. We will focus on such disorders that are caused by direct action of the SARS-CoV-2 virus on tissues, complement and coagulation system and on non-specific eruption of the systemic viral infection. Drug-induced reactions are only mentioned in the differential diagnoses. Although more systematic investigations are warranted, it comes clear that some symptoms are clinical signs of a milder COVID-19 course, while others are a red flag for a more severe course. Knowledge of the cutaneous manifestations of COVID-19 may help in early diagnosis, triage of patients and risk stratification. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Acro-ischemia; Androgenetic alopecia; COVID-19; Chilblain-like eruptions; Maculopapular rash; Purpuric rash; SARS-CoV-2; Urticaria
PMID:32390279DOI:10.1111/dth.13549
Cutaneous Signs in COVID-19 Patients: A Review.
Wollina U[SUP]1[/SUP], Karadağ AS[SUP]2[/SUP], Rowland-Payne C[SUP]3[/SUP], Chiriac A[SUP]4,[/SUP][SUP]5,[/SUP][SUP]6[/SUP], Lotti T[SUP]7[/SUP].
Author information
Abstract
COVID-19 pandemic caused by beta-coronavirus SARS-CoV-2 primarily affects the epithelium of the airways. With the increasing involvement of dermatologist in management of this crisis, cutaneous symptoms gained more and more attention. In this review we will describe cutaneous symptoms of patients of all ages in association with COVID-19. We will focus on such disorders that are caused by direct action of the SARS-CoV-2 virus on tissues, complement and coagulation system and on non-specific eruption of the systemic viral infection. Drug-induced reactions are only mentioned in the differential diagnoses. Although more systematic investigations are warranted, it comes clear that some symptoms are clinical signs of a milder COVID-19 course, while others are a red flag for a more severe course. Knowledge of the cutaneous manifestations of COVID-19 may help in early diagnosis, triage of patients and risk stratification. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Acro-ischemia; Androgenetic alopecia; COVID-19; Chilblain-like eruptions; Maculopapular rash; Purpuric rash; SARS-CoV-2; Urticaria
PMID:32390279DOI:10.1111/dth.13549