tetano
Editor, Senior Moderator
Dermatol Ther
. 2020 Nov 18.
doi: 10.1111/dth.14554. Online ahead of print.
Cutaneous and histopathological features of Coronavirus disease 2019 in pediatrics: A review article
Maryam Khalili[SUP] 1 [/SUP], Behzad Iranmanesh[SUP] 1 [/SUP], Saman Mohammadi[SUP] 1 [/SUP], Mahin Aflatoonian[SUP] 2 [/SUP]
Affiliations
Abstract
Prevalence of dermatologic manifestations of COVID-19 disease is estimated between 0.25 % and 3% in children and adolescents. In this review article, we decided to describe cutaneous and histopathological manifestations of COVID-19 infection in pediatrics. We searched published articles in PubMed database for key words of 'children" or "pediatric" and "cutaneous" or "dermatology "or "skin" and "COVID-19" or "SARS-CoV-2" or "Coronavirus disease 2019" in abstract or title from December of 2019 until September 2020. Finally, 38 articles were selected. The majority of patients were between 11-17 years old with predominantly male gender. Most of the patients were either asymptomatic or had a few general symptoms. Latency time from appearance of general symptoms to cutaneous ones was between 1 day to weeks. Skin lesions faded between 3 -88 days without any sequelae, spontaneously or with either topical or systemic corticosteroids. Skin manifestations were including chilblain-like (pseudochilblain), EM-like, dactylitis, acral erythema, acute urticaria, livedo reticularis, mottling, acro-ischemia, generalized maculopapular lesions, eyelid dermatitis, miliaria-like, varicelliform lesions, and petechiae and/or purpura. Kawa - COVID-19 patients were presented more frequently with cardiogenic shock, neurological symptoms, lymphocytopenia and thrombocytopenia as compared to classic Kawasaki's disease. Furthermore, more number of the cases were resistant to first-line of treatments This article is protected by copyright. All rights reserved.
Keywords: COVID-19; Cutaneous; Pathology; Pediatric.
. 2020 Nov 18.
doi: 10.1111/dth.14554. Online ahead of print.
Cutaneous and histopathological features of Coronavirus disease 2019 in pediatrics: A review article
Maryam Khalili[SUP] 1 [/SUP], Behzad Iranmanesh[SUP] 1 [/SUP], Saman Mohammadi[SUP] 1 [/SUP], Mahin Aflatoonian[SUP] 2 [/SUP]
Affiliations
- PMID: 33210417
- DOI: 10.1111/dth.14554
Abstract
Prevalence of dermatologic manifestations of COVID-19 disease is estimated between 0.25 % and 3% in children and adolescents. In this review article, we decided to describe cutaneous and histopathological manifestations of COVID-19 infection in pediatrics. We searched published articles in PubMed database for key words of 'children" or "pediatric" and "cutaneous" or "dermatology "or "skin" and "COVID-19" or "SARS-CoV-2" or "Coronavirus disease 2019" in abstract or title from December of 2019 until September 2020. Finally, 38 articles were selected. The majority of patients were between 11-17 years old with predominantly male gender. Most of the patients were either asymptomatic or had a few general symptoms. Latency time from appearance of general symptoms to cutaneous ones was between 1 day to weeks. Skin lesions faded between 3 -88 days without any sequelae, spontaneously or with either topical or systemic corticosteroids. Skin manifestations were including chilblain-like (pseudochilblain), EM-like, dactylitis, acral erythema, acute urticaria, livedo reticularis, mottling, acro-ischemia, generalized maculopapular lesions, eyelid dermatitis, miliaria-like, varicelliform lesions, and petechiae and/or purpura. Kawa - COVID-19 patients were presented more frequently with cardiogenic shock, neurological symptoms, lymphocytopenia and thrombocytopenia as compared to classic Kawasaki's disease. Furthermore, more number of the cases were resistant to first-line of treatments This article is protected by copyright. All rights reserved.
Keywords: COVID-19; Cutaneous; Pathology; Pediatric.