tetano
Editor, Senior Moderator
Dermatol Ther
. 2022 Jan 3;e15298.
doi: 10.1111/dth.15298. Online ahead of print.
Chilblain or Perniosis-like Skin Lesions in children during the COVID-19 pandemic: A Systematic Review of Articles
Hamideh Molaee[SUP] 1 [/SUP], Seyed Naser Emadi[SUP] 2 [/SUP], James Machoki N M'Imunya[SUP] 3 [/SUP], Esmat Davoudi-Monfared[SUP] 4 [/SUP], Asha Mohammed[SUP] 5 [/SUP], Zahra Razavi[SUP] 6 [/SUP]
Affiliations
Abstract
COVID toes or chilblain-like skin lesions represent a widespread and specific skin presentation in the feet attributed to COVID-19 infection. They may last for several months. We conducted this study to investigate chilblain-like lesions in children during the COVID-19 pandemic, any predisposition, location, clinical course, and prognosis. We searched Google Scholar, Scopus, and Medline (PubMed) databases using the following keywords: "Coronavirus" OR "COVID-19" AND "Chilblains" OR "Pernio" OR "Perniosis" OR "Children" OR "Cutaneous" OR "skin." The inclusion criteria were: studies that described the specific vascular skin lesion. studies that included patients that were aged > one month till 18 years. . Case reports, case series, retrospective or prospective cohort studies, case-control studies. Twenty-eight articles were included. The total number of children with CLL was 433. The mean age of children presenting CLL during the COVID-19 pandemic was estimated as 12.58 ± 2.15. Of note, 53.6% of them were male. The nasopharyngeal SARS-CoV-2 RT-PCR test and anti-SARS-CoV-2 antibodies were mostly negative for the virus. In conclusion, it is crucial to be familiar with various presentations of COVID-19 infection and their clinical significance to approach the earliest diagnosis, immediate treatment, estimate the prognosis and finally isolate the patients to prevent spreading. Chilblain-like lesions as a possible cutaneous presentation of COVID-19 in children may last several months with the indolent course.
Keywords: COVID toes; COVID-19; Chilblain; Children; Skin presentation.
. 2022 Jan 3;e15298.
doi: 10.1111/dth.15298. Online ahead of print.
Chilblain or Perniosis-like Skin Lesions in children during the COVID-19 pandemic: A Systematic Review of Articles
Hamideh Molaee[SUP] 1 [/SUP], Seyed Naser Emadi[SUP] 2 [/SUP], James Machoki N M'Imunya[SUP] 3 [/SUP], Esmat Davoudi-Monfared[SUP] 4 [/SUP], Asha Mohammed[SUP] 5 [/SUP], Zahra Razavi[SUP] 6 [/SUP]
Affiliations
- PMID: 34981615
- DOI: 10.1111/dth.15298
Abstract
COVID toes or chilblain-like skin lesions represent a widespread and specific skin presentation in the feet attributed to COVID-19 infection. They may last for several months. We conducted this study to investigate chilblain-like lesions in children during the COVID-19 pandemic, any predisposition, location, clinical course, and prognosis. We searched Google Scholar, Scopus, and Medline (PubMed) databases using the following keywords: "Coronavirus" OR "COVID-19" AND "Chilblains" OR "Pernio" OR "Perniosis" OR "Children" OR "Cutaneous" OR "skin." The inclusion criteria were: studies that described the specific vascular skin lesion. studies that included patients that were aged > one month till 18 years. . Case reports, case series, retrospective or prospective cohort studies, case-control studies. Twenty-eight articles were included. The total number of children with CLL was 433. The mean age of children presenting CLL during the COVID-19 pandemic was estimated as 12.58 ± 2.15. Of note, 53.6% of them were male. The nasopharyngeal SARS-CoV-2 RT-PCR test and anti-SARS-CoV-2 antibodies were mostly negative for the virus. In conclusion, it is crucial to be familiar with various presentations of COVID-19 infection and their clinical significance to approach the earliest diagnosis, immediate treatment, estimate the prognosis and finally isolate the patients to prevent spreading. Chilblain-like lesions as a possible cutaneous presentation of COVID-19 in children may last several months with the indolent course.
Keywords: COVID toes; COVID-19; Chilblain; Children; Skin presentation.