Debate over Seasonal Flu

[tropical]

AD - Dr. Niman comm.:
"The high concentration at one facility suggests the H274Y is evolutionarily fit, although there is a possibility that these patients were being treated with Tamiflu. However, reports from Europe, where Tamiflu resistance is high, indicate such cases were not treated with Tamiflu."
...
"... These cases could pose a serious health problem in at risk populations because Tamiflu is rendered useless by H274Y, and the recent H1N1 isolates in the US and Europe have been the Brisbane strain, which is not well recognized by the current trivalent vaccine. The match failures for H3N2 and influenza B, coupled with the poor match for Brisbane H1N1 has been associated with rapid spread of influenza in the United States, which has generated an MMWR report this week, and the second CDC news conference in a week. ..."

Seems that we begin to have more serious changings in already human flu strains, than by humanization of the H5N1, at the moment.

 

[gsgs]

Re: :::Emergence of seasonal influenza viruses type A/H1N1 with:::

Re: :::Emergence of seasonal influenza viruses type A/H1N1 with:::

when are the weekly flu-pages updated BTW. ?
I remember Germany was updated last Wednesday.

CDC ? EISS ? flunet ? Sentinelles network website France ?
others ?

 

[gsgs]

Re: :::Emergence of seasonal influenza viruses type A/H1N1 with:::

Re: :::Emergence of seasonal influenza viruses type A/H1N1 with:::

the first H1N1 virus from USA 2008 is uploaded to lanl.
A/Pennsylvania/01/2008(H1N1)
It is sensitive to Amantadine and Oseltamivir, close to the 2009-vaccine strain
A/Brisbane/59/07(H1N1).
It strangely misses 3 of the Brisbane -markers at the beginning of HA
but coincides with the other markers.
No other virus in the database with this property.
How could this happen ?
It mutated back to the pre-2005 strain at exactly these (synonymous) positions ? Seems unlikely.
It is a side-strain which developed before 2005 together with Brisbane/59
from an ancestor which didn't have the markers, which all the other viruses
developed later ? It is probably too much similar to Brisbane/59 for that.
Only 3 other differences in HA.
It was a short recombination from a double infection with
Brisbane/59 - like and one of the H1N1 viruses dominant
in USA last season ?
But marker 3 is there, 1,2,4 are missing.

where did it come from, how did it evolve ???

 

[tropical]

Re: :::Emergence of seasonal influenza viruses type A/H1N1 with:::

Re: :::Emergence of seasonal influenza viruses type A/H1N1 with:::

"where did it come from, how did it evolve ???"

Labs hard work ...

 

[mixin]

Re: :::Emergence of seasonal influenza viruses type A/H1N1 with:::

Re: :::Emergence of seasonal influenza viruses type A/H1N1 with:::

"where did it come from, how did it evolve ???"

Labs hard work ...

But rarely do they escape. Like recently in the Shope Lab (level 4) at the University of Texas, when the doors failed twice . We were assured that everything was contained. In addition to Avian Influenza and Omsk hemorrhagic, 6 other unnamed experiments were being conducted.

http://news.galvestondailynews.com/story.lasso?ewcd=fee6b3293a684d92

 

[Malcolm]

Re: :::Emergence of seasonal influenza viruses type A/H1N1 with:::

Re: :::Emergence of seasonal influenza viruses type A/H1N1 with:::

But rarely do they escape. Like recently in the Shope Lab (level 4) at the University of Texas, when the doors failed twice . We were assured that everything was contained. In addition to Avian Influenza and Omsk hemorrhagic, 6 other unnamed experiments were being conducted.

http://news.galvestondailynews.com/story.lasso?ewcd=fee6b3293a684d92

QUOTE ---"We were assured that everything was contained."

Assured by who? "A trusted authority?" There aren't any!

Assured by what? Absence of dead people piling up?

Assured by strict oversight and control of biolabs? THERE IS NONE.

Here is the most recent (somehow SILENCED) biolab whistleblower:

http://www.sunshine-project.org/

 

[mixin]

Re: Debate over Seasonal Flu

Here: straight from the spokeswoman's mouth

Both diseases are highly deadly in humans, but no people were in the two rooms connected by the door when it failed, said university spokeswoman Chris Comer.

In addition, the disease-causing bugs were behind barriers of their own within the lab, so none escaped, Comer said.

?It?s containment within containment within containment and negative air pressure throughout,? Comer said.

 

[HenryN]

Re: Debate over Seasonal Flu

This thread is drifting off topic. The is NO DATA to remotely indoacte ANY of the changes are due to lab experiments.

Flu evolves, and there is agreat deal of evidence that the evolution is NOT random and do NOT involve de novo mutations.

There is another thread for Martian Chronicals.

Please stay on topic.

 

[gsgs]

Re: Debate over Seasonal Flu

I updated the CDC seasonal data with graphics and correlation coefficients:

http://www.setbb.com/fluwiki2/viewtopic.php?p=746&mforum=fluwiki2#746


Some years there is H1N1, some years H3N2 while the other
one is almost absent. The same is true for special strains
within one serotype. So the Brisbane strain or the Amantadine
resistant strains might disappear in some years
and/or come back later. There is no proof yet that it's
due to drug use, although some evidence.
If it goes as with Amantadine-resistance, then we have
95% Oseltamivir-resistant next year !