• FluTrackers.com Inc. does not provide medical advice. Information on this web site is collected from various internet resources, and the FluTrackers board of directors makes no warranty to the safety, efficacy, correctness or completeness of the information posted on this site by any author or poster. The information collated here is for instructional and/or discussion purposes only and is NOT intended to diagnose or treat any disease, illness, or other medical condition. Every individual reader or poster should seek advice from their personal physician/healthcare practitioner before considering or using any interventions that are discussed on this website. By continuing to access this website you agree to consult your personal physican before using any interventions posted on this website, and you agree to hold harmless FluTrackers.com Inc., the board of directors, the members, and all authors and posters for any effects from use of any medication, supplement, vitamin or other substance, device, intervention, etc. mentioned in posts on this website, or other internet venues referenced in posts on this website.
  • We are not asking for any donations. Do not donate to any entity who says they are raising funds for us.

Deadly pneumonia caused by super-bugs on rise: study

Shiloh

Editor, Senior Moderator
Source: http://www.reuters.com/article/healthNews/idUSTRE54I7I520090519

Deadly pneumonia caused by super-bugs on rise: study
Tue May 19, 2009 7:08pm EDT

Email | Print |


LONDON (Reuters) - Deadly pneumonia caused by so-called superbugs are spreading outside hospitals and represent a growing threat to the public, U.S. researchers warned on Wednesday.

Making the problem more worrying is the recent H1N1 flu outbreak because the "super-bug" pneumonia most commonly appears following an influenza-like illness, Alicia Hidron of the Emory University School of Medicine in Atlanta reported.

Methicillin-resistant Staphylococcus aureus (MRSA) infections can range from boils to more severe infections of the blood, lungs and the sites of surgery. Such infections can often be treated only with expensive intravenous antibiotics.

Most cases are associated with hospitals, nursing homes or other health care facilities but infections acquired in the wider community are increasing, the researcher noted.

"Community-acquired MRSA infections are no longer restricted to certain risk groups or to the geographic areas where outbreaks first occurred," they wrote in the journal Lancet Infectious Diseases.

"They now occur widely both in the community as well as health care facilities and have been reported on every continent."

As these superbugs spread in communities, more pneumonia cases are likely -- and the researchers said these may have mortality rates of more than 50 percent.

"However, the overall incidence of community-acquired MRSA pneumonia remains unknown," the researchers wrote.

In their analysis, Hidron and colleagues looked at two U.S. cases caused by a specific MRSA strain that is a culprit behind many superbug infections in the United States.

They reported the pneumonia usually features high fever and low blood pressure with rapid progression to septic shock -- a widespread infection that sends the whole body into a tailspin -- and an urgent need for mechanical ventilation.

The researchers said they do not know why community-acquired MRSA pneumonia appears so lethal but noted the bacteria that cause it are more susceptible to antibiotics than hospital-acquired infections.

"The best treatment of this ... disease has not been defined," they wrote.

(Reporting by Michael Kahn; Editing by Maggie Fox and Jon Hemming)
 
Re: Deadly pneumonia caused by super-bugs on rise: study

There is another, related article, from the Lancet available at the link below:

http://download.thelancet.com/flatcontentassets/H1N1-flu/pathogenesis/pathogenesis-6.pdf

It's a .pdf so I can't cut and paste any of it. But, it describes the relationship between influenza and secondary bacterial pneumonias using clinical descriptions of patients from the 1918 pandemic as an introduction. It goes on to discuss the implications for pandemic planning. A great read.
 
Re: Deadly pneumonia caused by super-bugs on rise: study

Source: http://www.redorbit.com/news/health/1692629/new_mrsa_strain_may_be_deadly_for_flu_patients/

New MRSA Strain May Be Deadly For Flu Patients

Posted on: Wednesday, 20 May 2009, 12:40 CDT

Researchers say that an antibiotic-resistant strain of the bacterium MRSA appears to be making flu patients susceptible to a deadly form of pneumonia.

More worrisome still is the fact that the new community acquired MRSA (CA-MRSA) is not limited to hospital settings unlike most commonly known strains of the superbug.

Publishing their report in the medical journal Lancet Infectious Diseases, a group of researchers from Emory University School of Medicine in Atlanta say that the disease may have a mortality rate as high as 50 percent amongst those who contract it.

The team also expressed concerns that the spread of swine flu could exacerbate the problem, as some of their results seemed to indicate that CA-MRSA occurs more frequent in people who are already sick with the flu.

Just how big a threat the new microbe poses, however, is not yet clear. Researchers say there is not yet enough data available to accurately estimate the prevalence of CA-MRSA in the community at large.

Occurring most frequently in healthcare facilities such as hospitals and nursing homes, the symptoms of typical MRSA strains can range from painful boils to infections in the lungs, blood and surgical wounds.
?Community-acquired MRSA infections are no longer restricted to certain risk groups or to the geographic areas where outbreaks first occurred,? wrote the research team.

?They now occur widely both in the community as well as health care facilities and have been reported on every continent.?

The group?s study was based on an examination of two cases in the U.S. Both patients contracted bacterial pneumonia and exhibited high fever and low blood pressure before going into septic shock?a serious medical condition involving systemic bacterial infection. Fatality rates for septic shock are generally in the 50 percent range.

Both of the patients examined in the study eventually recovered.

Researchers say they are still not sure what makes the bacterium so dangerous. They believe, however, that it originated in Australia in the 1990?s, but at that time only seemed to cause relatively mild problems with skin and soft tissue.

One positive sign that the researchers observed was that the new strain does appear to be more susceptible to antibiotics than standard MRSA infections.

?Bacterial pneumonia following influenza can be very serious and in some cases fatal,? said Professor Mark Enright, an infectious disease expert at Imperial College London.

?The emergence of pandemic influenza and increased prevalence of CA-MRSA in many countries may cause increased morbidity and mortality in infected individuals.?

Professor Ron Cutler of Queen Mary University of London added, ?In the past, respiratory tract infections with MRSA tended to be in the elderly in a hospital ward? [but] the CA strains are able because of their increased toxic potential to infect a younger population.?

Professor Richard James of the University of Nottingham worries that this more dangerous form of MRSA could eventually become as widespread as the version that has plagued hospitals around the world since the 1990?s.

?It took [us] 13 years to get to grips with the hospital-acquired MRSA infection?we are not equipped to deal with large numbers of CA-MRSA infections in the community.?

---

On the Net:

* Lancet Infectious Diseases
 
Back
Top