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Cytometry A. Handling and Processing of Blood Specimens from Patients with COVID-19 for Safe Studies on Cell Phenotype and Cytokine Storm

tetano

Editor, Senior Moderator
Cytometry A. 2020 Apr 10. doi: 10.1002/cyto.a.24009. [Epub ahead of print]
Handling and Processing of Blood Specimens from Patients with COVID-19 for Safe Studies on Cell Phenotype and Cytokine Storm.


Cossarizza A[SUP]1,[/SUP][SUP]2[/SUP], Gibellini L[SUP]2[/SUP], De Biasi S[SUP]2[/SUP], Lo Tartaro D[SUP]2[/SUP], Mattioli M[SUP]2[/SUP], Paolini A[SUP]2[/SUP], Fidanza L[SUP]2[/SUP], Bellinazzi C[SUP]2[/SUP], Borella R[SUP]2[/SUP], Castaniere I[SUP]3[/SUP], Meschiari M[SUP]4[/SUP], Sita M[SUP]5[/SUP], Manco G[SUP]6[/SUP], Clini E[SUP]3[/SUP], Gelmini R[SUP]6[/SUP], Girardis M[SUP]5[/SUP], Guaraldi G[SUP]4[/SUP], Mussini C[SUP]4[/SUP].

Author information




Abstract

The pandemic caused by severe acute respiratory syndrome coronavirus 2 heavily involves all those working in a laboratory. Samples from known infected patients or donors who are considered healthy can arrive, and a colleague might be asymptomatic but able to transmit the virus. Working in a clinical laboratory is posing several safety challenges. Few years ago, International Society for Advancement of Cytometry published guidelines to safely analyze and sort human samples that were revised in these days. We describe the procedures that we have been following since the first patient appeared in Italy, which have only slightly modified our standard one, being all human samples associated with risks.
? 2020 International Society for Advancement of Cytometry.



KEYWORDS:

Covid-19; SARS-CoV-2; biosafety; coronavirus; cytokines; cytometry


PMID:32275124DOI:10.1002/cyto.a.24009
 
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