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Cytokine and chemokine response in children with the 2009 pandemic influenza A (H1N1) virus infection

tetano

Editor, Senior Moderator
Eur J Clin Microbiol Infect Dis. 2010 Sep 6. [Epub ahead of print]
Cytokine and chemokine response in children with the 2009 pandemic influenza A (H1N1) virus infection.

Takano T, Tajiri H, Kashiwagi Y, Kimura S, Kawashima H.

Department of Pediatrics, Osaka General Medical Center, 3-1-56 Bandai-Higashi, Sumiyoshi-ku, Osaka, 558-8558, Japan, takano@gh.opho.jp.
Abstract

We report the systemic cytokine and chemokine response in children with the 2009 pandemic influenza A (H1N1) virus infection. In patients with pneumonia, the serum levels of IFN-gamma and IL-5 were significantly higher than those in patients without pneumonia. This tendency was also present for IL-6, IL-8, IL-10, IL-13, and MCP-1 in patients with pneumonia. Among patients with pneumonia, the levels of MCP-1 were significantly higher in the group of patients with pneumonia with severe respiratory failure than patients with mild pneumonia.

PMID: 20820834 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/20820834
 
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