tetano
Editor, Senior Moderator
Curr Pharmacol Rep
. 2021 Feb 18;1-6.
doi: 10.1007/s40495-021-00253-w. Online ahead of print.
Efficacy and Safety of New and Emerging Drugs for COVID-19: Favipiravir and Dexamethasone
Shivani Sood[SUP] 1 [/SUP], Gurpreet Kaur Bhatia[SUP] 2 [/SUP], Prachi Seth[SUP] 1 [/SUP], Pawan Kumar[SUP] 3 [/SUP], Jagjit Kaur[SUP] 4 [/SUP], Vidisha Gupta[SUP] 5 [/SUP], Sandeep Punia[SUP] 6 [/SUP], Hardeep Singh Tuli[SUP] 7 [/SUP]
Affiliations
Abstract
Purpose of review: The widespread respiratory disease of virus known as severe acute respiratory syndrome-coronavirus 2019 (SAR-CoV-2) had infected more than 200 countries and caused pandemic and havoc in the world.
Recent findings: The genome of the virus was sequenced rapidly to study its mechanism, epidemiology, drugs, and vaccines. Many drugs and vaccines are being studied by researchers to treat and prevent the SARS-CoV-2. Favipiravir and dexamethasone are repurposed drugs which showed therapeutic potential and pharmaceutical efficacy against SARS-CoV-2.
Summary: The review describes the path of favipiravir and dexamethasone from chemistry to mechanisms of action to combat SARS-CoV-2. In addition, the potential side effects are also summarized to study their potential to control corona virus 2019.
Keywords: Coronavirus 2019; Dexamethasone; Epidemiology; Favipiravir; Severe acute respiratory syndrome.
. 2021 Feb 18;1-6.
doi: 10.1007/s40495-021-00253-w. Online ahead of print.
Efficacy and Safety of New and Emerging Drugs for COVID-19: Favipiravir and Dexamethasone
Shivani Sood[SUP] 1 [/SUP], Gurpreet Kaur Bhatia[SUP] 2 [/SUP], Prachi Seth[SUP] 1 [/SUP], Pawan Kumar[SUP] 3 [/SUP], Jagjit Kaur[SUP] 4 [/SUP], Vidisha Gupta[SUP] 5 [/SUP], Sandeep Punia[SUP] 6 [/SUP], Hardeep Singh Tuli[SUP] 7 [/SUP]
Affiliations
- PMID: 33619447
- PMCID: PMC7889701
- DOI: 10.1007/s40495-021-00253-w
Abstract
Purpose of review: The widespread respiratory disease of virus known as severe acute respiratory syndrome-coronavirus 2019 (SAR-CoV-2) had infected more than 200 countries and caused pandemic and havoc in the world.
Recent findings: The genome of the virus was sequenced rapidly to study its mechanism, epidemiology, drugs, and vaccines. Many drugs and vaccines are being studied by researchers to treat and prevent the SARS-CoV-2. Favipiravir and dexamethasone are repurposed drugs which showed therapeutic potential and pharmaceutical efficacy against SARS-CoV-2.
Summary: The review describes the path of favipiravir and dexamethasone from chemistry to mechanisms of action to combat SARS-CoV-2. In addition, the potential side effects are also summarized to study their potential to control corona virus 2019.
Keywords: Coronavirus 2019; Dexamethasone; Epidemiology; Favipiravir; Severe acute respiratory syndrome.