tetano
Editor, Senior Moderator
Curr Pediatr Rep
. 2021 Oct 22;1-11.
doi: 10.1007/s40124-021-00258-5. Online ahead of print.
Short-term Cardiovascular Complications of Multi-system Inflammatory Syndrome in Children (MIS-C) in Adolescents and Children
Omar I Hejazi[SUP] 1 [/SUP], Yue-Hin Loke[SUP] 2 3 [/SUP], Ashraf S Harahsheh[SUP] 2 3 [/SUP]
Affiliations
Abstract
Purpose of review: We provide the readers with a review of cardiac complications in children with multi-system inflammatory syndrome in children (MIS-C) and its short-term outcomes.
Recent findings: Recent reports described the acute cardiac manifestations of MIS-C in children and provided a glimpse of the short-term outcomes.
Summary: Children with MIS-C have been reported to acutely have variable degrees of cardiac findings including abnormal cardiac enzymes, abnormal electrocardiographs, decreased systolic function, coronary artery abnormalities from coronary dilation to giant aneurysms, mitral valve regurgitation, tricuspid valve regurgitation, aortic valve insufficiency, pericardial effusion, diastolic dysfunction, abnormal cardiac strain, and abnormal cardiac MRI. The majority of these abnormalities resolved during short-term follow-up. Further studies are needed to assess if transient or persistent cardiac complications are associated with long-term adverse cardiac events in children with MIS-C.
Supplementary information: The online version contains supplementary material available at 10.1007/s40124-021-00258-5.
Keywords: 2019 coronavirus disease (COVID-19) pandemic; Coronary artery aneurysm; Multi-system inflammatory syndrome in children (MIS-C); Myocarditis; Pediatric cardiology; Pediatric multisystem inflammatory syndrome temporally associated with COVID-19 (PMIS).
. 2021 Oct 22;1-11.
doi: 10.1007/s40124-021-00258-5. Online ahead of print.
Short-term Cardiovascular Complications of Multi-system Inflammatory Syndrome in Children (MIS-C) in Adolescents and Children
Omar I Hejazi[SUP] 1 [/SUP], Yue-Hin Loke[SUP] 2 3 [/SUP], Ashraf S Harahsheh[SUP] 2 3 [/SUP]
Affiliations
- PMID: 34703656
- PMCID: PMC8531914
- DOI: 10.1007/s40124-021-00258-5
Abstract
Purpose of review: We provide the readers with a review of cardiac complications in children with multi-system inflammatory syndrome in children (MIS-C) and its short-term outcomes.
Recent findings: Recent reports described the acute cardiac manifestations of MIS-C in children and provided a glimpse of the short-term outcomes.
Summary: Children with MIS-C have been reported to acutely have variable degrees of cardiac findings including abnormal cardiac enzymes, abnormal electrocardiographs, decreased systolic function, coronary artery abnormalities from coronary dilation to giant aneurysms, mitral valve regurgitation, tricuspid valve regurgitation, aortic valve insufficiency, pericardial effusion, diastolic dysfunction, abnormal cardiac strain, and abnormal cardiac MRI. The majority of these abnormalities resolved during short-term follow-up. Further studies are needed to assess if transient or persistent cardiac complications are associated with long-term adverse cardiac events in children with MIS-C.
Supplementary information: The online version contains supplementary material available at 10.1007/s40124-021-00258-5.
Keywords: 2019 coronavirus disease (COVID-19) pandemic; Coronary artery aneurysm; Multi-system inflammatory syndrome in children (MIS-C); Myocarditis; Pediatric cardiology; Pediatric multisystem inflammatory syndrome temporally associated with COVID-19 (PMIS).