tetano
Editor, Senior Moderator
Curr Med Imaging
. 2021 Feb 17.
doi: 10.2174/1573405617666210218092751. Online ahead of print.
A Comparison of CT Manifestations between Coronavirus Disease 2019 (COVID-19) and Other Types of Viral Pneumonia
Haixia Mao[SUP] 1 [/SUP], Xiaoshan Li[SUP] 2 [/SUP], Xiaoming Lin[SUP] 3 [/SUP], Lijuan Zhou[SUP] 1 [/SUP], Xiuping Zhang[SUP] 1 [/SUP], Yang Cao[SUP] 4 [/SUP], Yilun Jiang[SUP] 5 [/SUP], Hongwei Chen[SUP] 1 [/SUP], Xiangming Fang[SUP] 1 [/SUP], Lan Gu[SUP] 3 [/SUP]
Affiliations
Abstract
Background: Though imaging manifestations of COVID-19 and other types of viral pneumonia are similar, their clinical treatment methods differ. Accurate, non-invasive diagnostic methods using CT imaging can help developing an optimal therapeutic regimen for both conditions.
Objectives: To compare the initial CT imaging features in COVID-19 with those in other types of viral pneumonia.
Methods: Clinical and imaging data of 51 patients with COVID-19 and 69 with other types of viral pneumonia were retrospectively studied. All significant imaging features (Youden index >0.3) were included for constituting the combined criteria for COVID-19 diagnosis, composed of two or more imaging features with a parallel model. McNemar's chi-square test or Fisher's exact test was used to compare the validity indices (sensitivity and specificity) among various criteria.
Results: Ground glass opacities (GGO) dominated density, peripheral distribution, unilateral lung, clear margin of lesion, rounded morphology, long axis parallel to the pleura, vascular thickening, and crazy-paving pattern were more common in COVID-19 (p <0.05). Consolidation-dominated density, both central and peripheral distribution, bilateral lung, indistinct margin of lesion, tree-in-bud pattern, mediastinal or hilar lymphadenectasis, pleural effusion, and pleural thickening were more common in other types of viral pneumonia (p < 0.05). GGO-dominated density or long axis parallel to the pleura (with the highest sensitivity), and GGO-dominated density or long axis parallel to the pleura or vascular thickening (with the highest specificity) are good combined criteria of COVID-19.
Conclusion: The initial CT imaging features are helpful for differential diagnosis between COVID-19 and other types of viral pneumonia.
Keywords: Ground glass Opacities; X-ray computed; coronavirus disease 2019; differential diagnosis; manifestation; other types of viral pneumonia; tomography.
. 2021 Feb 17.
doi: 10.2174/1573405617666210218092751. Online ahead of print.
A Comparison of CT Manifestations between Coronavirus Disease 2019 (COVID-19) and Other Types of Viral Pneumonia
Haixia Mao[SUP] 1 [/SUP], Xiaoshan Li[SUP] 2 [/SUP], Xiaoming Lin[SUP] 3 [/SUP], Lijuan Zhou[SUP] 1 [/SUP], Xiuping Zhang[SUP] 1 [/SUP], Yang Cao[SUP] 4 [/SUP], Yilun Jiang[SUP] 5 [/SUP], Hongwei Chen[SUP] 1 [/SUP], Xiangming Fang[SUP] 1 [/SUP], Lan Gu[SUP] 3 [/SUP]
Affiliations
- PMID: 33602104
- DOI: 10.2174/1573405617666210218092751
Abstract
Background: Though imaging manifestations of COVID-19 and other types of viral pneumonia are similar, their clinical treatment methods differ. Accurate, non-invasive diagnostic methods using CT imaging can help developing an optimal therapeutic regimen for both conditions.
Objectives: To compare the initial CT imaging features in COVID-19 with those in other types of viral pneumonia.
Methods: Clinical and imaging data of 51 patients with COVID-19 and 69 with other types of viral pneumonia were retrospectively studied. All significant imaging features (Youden index >0.3) were included for constituting the combined criteria for COVID-19 diagnosis, composed of two or more imaging features with a parallel model. McNemar's chi-square test or Fisher's exact test was used to compare the validity indices (sensitivity and specificity) among various criteria.
Results: Ground glass opacities (GGO) dominated density, peripheral distribution, unilateral lung, clear margin of lesion, rounded morphology, long axis parallel to the pleura, vascular thickening, and crazy-paving pattern were more common in COVID-19 (p <0.05). Consolidation-dominated density, both central and peripheral distribution, bilateral lung, indistinct margin of lesion, tree-in-bud pattern, mediastinal or hilar lymphadenectasis, pleural effusion, and pleural thickening were more common in other types of viral pneumonia (p < 0.05). GGO-dominated density or long axis parallel to the pleura (with the highest sensitivity), and GGO-dominated density or long axis parallel to the pleura or vascular thickening (with the highest specificity) are good combined criteria of COVID-19.
Conclusion: The initial CT imaging features are helpful for differential diagnosis between COVID-19 and other types of viral pneumonia.
Keywords: Ground glass Opacities; X-ray computed; coronavirus disease 2019; differential diagnosis; manifestation; other types of viral pneumonia; tomography.