tetano
Editor, Senior Moderator
Cureus
. 2022 Jan 13;14(1):e21188.
doi: 10.7759/cureus.21188. eCollection 2022 Jan.
Severe Acute Respiratory Syndrome Coronavirus-2 Pneumonia Presenting Concomitantly With Purpura Fulminans: A Case Report
Giulio Ciprian[SUP] 1 [/SUP]
Affiliations
Abstract
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that has been extensively described in its most common presentations. Its pathogenetic process is poorly understood, although it is theorized that endothelial damage and inflammation play a central role. Its prothrombotic nature affects multiple organs, including lungs, kidneys, and the central nervous system. Rarer are cutaneous presentations that can be triggered or displayed concomitantly with COVID-19. Purpura fulminans is a life-threatening syndrome that results in skin thrombosis and hemorrhagic infarction. While its association is explicit in critically ill patients with sepsis, few or rare cases have been described to be linked with COVID-19. In this report, we present a case of a critically ill patient with COVID-19 who showed signs of purpura fulminans while in the intensive care unit.
Keywords: acute infectious purpura fulminans; coronavirus disease (covid-19); covid and purpura fulminans; covid-19; pulmonary critical care.
. 2022 Jan 13;14(1):e21188.
doi: 10.7759/cureus.21188. eCollection 2022 Jan.
Severe Acute Respiratory Syndrome Coronavirus-2 Pneumonia Presenting Concomitantly With Purpura Fulminans: A Case Report
Giulio Ciprian[SUP] 1 [/SUP]
Affiliations
- PMID: 35186515
- PMCID: PMC8844178
- DOI: 10.7759/cureus.21188
Abstract
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that has been extensively described in its most common presentations. Its pathogenetic process is poorly understood, although it is theorized that endothelial damage and inflammation play a central role. Its prothrombotic nature affects multiple organs, including lungs, kidneys, and the central nervous system. Rarer are cutaneous presentations that can be triggered or displayed concomitantly with COVID-19. Purpura fulminans is a life-threatening syndrome that results in skin thrombosis and hemorrhagic infarction. While its association is explicit in critically ill patients with sepsis, few or rare cases have been described to be linked with COVID-19. In this report, we present a case of a critically ill patient with COVID-19 who showed signs of purpura fulminans while in the intensive care unit.
Keywords: acute infectious purpura fulminans; coronavirus disease (covid-19); covid and purpura fulminans; covid-19; pulmonary critical care.