tetano
Editor, Senior Moderator
Cureus
. 2022 May 20;14(5):e25170.
doi: 10.7759/cureus.25170. eCollection 2022 May.
Reversible Autoimmune Cardiomyopathy Secondary to a Vaccine-Induced Multisystem Inflammatory Syndrome
Ana P Urena Neme[SUP] 1 [/SUP], Elmer R De Camps Martinez[SUP] 1 [/SUP], Constangela Matos Noboa[SUP] 1 [/SUP], Miguel A Rodriguez Guerra[SUP] 2 [/SUP], Pedro Ureña[SUP] 3 [/SUP]
Affiliations
Abstract
The Dominican government started an early booster protocol, including a heterogeneous vaccination sequence needed based on availability. We report a case of a 25-year-old male who presented with jaundice, and vomiting for 6 days, associated with maculopapular rash (Mucocutaneous features), elevated pro-B-type natriuretic peptide (pro-BNP), erythrocyte sedimentation rate (ESR), transaminitis (> 1000 U/L), thrombocytopenia, echocardiogram evidenced stigmata of heart failure after his third dose of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. He was started on steroids and immunoglobulin therapy for multisystemic organ failure syndrome. A significant improvement was noticed, then was discharge; in the post-discharge clinic, he was asymptomatic, inflammatory markers improved, and the echocardiogram showed a recovered ejection fraction. An accurate anamnesis, including a proper chronologic gathering of the events, is essential to recognize a vaccine-multisystem inflammatory syndrome; its prompt assessment and therapy would directly improve the outcome.
Keywords: covid vaccination booster; multisystem inflammatory syndrome (mis); multisystem inflammatory syndrome by vaccination (mis-v); reversible autoimmune cardiomyopathy; sars-cov-2.
. 2022 May 20;14(5):e25170.
doi: 10.7759/cureus.25170. eCollection 2022 May.
Reversible Autoimmune Cardiomyopathy Secondary to a Vaccine-Induced Multisystem Inflammatory Syndrome
Ana P Urena Neme[SUP] 1 [/SUP], Elmer R De Camps Martinez[SUP] 1 [/SUP], Constangela Matos Noboa[SUP] 1 [/SUP], Miguel A Rodriguez Guerra[SUP] 2 [/SUP], Pedro Ureña[SUP] 3 [/SUP]
Affiliations
- PMID: 35747051
- PMCID: PMC9206861
- DOI: 10.7759/cureus.25170
Abstract
The Dominican government started an early booster protocol, including a heterogeneous vaccination sequence needed based on availability. We report a case of a 25-year-old male who presented with jaundice, and vomiting for 6 days, associated with maculopapular rash (Mucocutaneous features), elevated pro-B-type natriuretic peptide (pro-BNP), erythrocyte sedimentation rate (ESR), transaminitis (> 1000 U/L), thrombocytopenia, echocardiogram evidenced stigmata of heart failure after his third dose of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. He was started on steroids and immunoglobulin therapy for multisystemic organ failure syndrome. A significant improvement was noticed, then was discharge; in the post-discharge clinic, he was asymptomatic, inflammatory markers improved, and the echocardiogram showed a recovered ejection fraction. An accurate anamnesis, including a proper chronologic gathering of the events, is essential to recognize a vaccine-multisystem inflammatory syndrome; its prompt assessment and therapy would directly improve the outcome.
Keywords: covid vaccination booster; multisystem inflammatory syndrome (mis); multisystem inflammatory syndrome by vaccination (mis-v); reversible autoimmune cardiomyopathy; sars-cov-2.