tetano
Editor, Senior Moderator
Cureus
. 2023 Jan 17;15(1):e33897.
doi: 10.7759/cureus.33897. eCollection 2023 Jan.
Pemphigus Vulgaris Possibly Associated with COVID-19 Infection
Yul Hee Kim[SUP] 1 [/SUP], Hee Young Kang[SUP] 1 [/SUP]
Affiliations
Abstract
Pemphigus vulgaris (PV) represents damage to epidermal keratinocytes, resulting in acantholysis due to the production of autoantibodies against desmoglein-1 and desmoglein-3. Autoimmune blistering disorders such as pemphigus vulgaris or bullous pemphigoid that develop following coronavirus disease 2019 (COVID-19) have been reported in several studies. Herein, we report a case of PV onset following COVID-19 infection in a 17-year-old female, demonstrating --the potential pathogenic capacity of SARS-CoV-2 to develop PV.
Keywords: autoimmune bullous disease; covid-19; keratinocyte; pemphigus vulgaris; sars-cov-2 spike protein.
. 2023 Jan 17;15(1):e33897.
doi: 10.7759/cureus.33897. eCollection 2023 Jan.
Pemphigus Vulgaris Possibly Associated with COVID-19 Infection
Yul Hee Kim[SUP] 1 [/SUP], Hee Young Kang[SUP] 1 [/SUP]
Affiliations
- PMID: 36819405
- PMCID: PMC9935475
- DOI: 10.7759/cureus.33897
Abstract
Pemphigus vulgaris (PV) represents damage to epidermal keratinocytes, resulting in acantholysis due to the production of autoantibodies against desmoglein-1 and desmoglein-3. Autoimmune blistering disorders such as pemphigus vulgaris or bullous pemphigoid that develop following coronavirus disease 2019 (COVID-19) have been reported in several studies. Herein, we report a case of PV onset following COVID-19 infection in a 17-year-old female, demonstrating --the potential pathogenic capacity of SARS-CoV-2 to develop PV.
Keywords: autoimmune bullous disease; covid-19; keratinocyte; pemphigus vulgaris; sars-cov-2 spike protein.