tetano
Editor, Senior Moderator
Cureus
. 2021 Nov 17;13(11):e19655.
doi: 10.7759/cureus.19655. eCollection 2021 Nov.
Occurrence of Guillain-Barre Syndrome During the Initial Symptomatic Phase of COVID-19 Disease: Coincidence or Consequence?
Rui Seixas[SUP] 1 [/SUP], David Campoamor[SUP] 1 [/SUP], João Lopes[SUP] 1 [/SUP], Teresa Bernardo[SUP] 1 [/SUP], Hipólito Nzwalo[SUP] 2 3 [/SUP], Dulce Pascoalinho[SUP] 4 [/SUP]
Affiliations
Abstract
Viral infections are frequently present before the clinical manifestation of Guillain-Barre syndrome (GBS). Multiple studies on coronaviruses have shown that these viruses have neurotropic characteristics, and their molecular mimicry can induce inflammatory demyelinating neuropathy. Herein, we describe a case of a GBS in an 85-year-old patient infected with SARS-CoV-2, manifested with acute progressive symmetric ascending quadriparesis, urinary dysautonomia, and dysphagia, who responded well to treatment with intravenous human immunoglobulin.
Keywords: covid-19; guillain barre syndrome; neurotropic virus; viral infections; viral mimicry.
. 2021 Nov 17;13(11):e19655.
doi: 10.7759/cureus.19655. eCollection 2021 Nov.
Occurrence of Guillain-Barre Syndrome During the Initial Symptomatic Phase of COVID-19 Disease: Coincidence or Consequence?
Rui Seixas[SUP] 1 [/SUP], David Campoamor[SUP] 1 [/SUP], João Lopes[SUP] 1 [/SUP], Teresa Bernardo[SUP] 1 [/SUP], Hipólito Nzwalo[SUP] 2 3 [/SUP], Dulce Pascoalinho[SUP] 4 [/SUP]
Affiliations
- PMID: 34976451
- PMCID: PMC8678953
- DOI: 10.7759/cureus.19655
Abstract
Viral infections are frequently present before the clinical manifestation of Guillain-Barre syndrome (GBS). Multiple studies on coronaviruses have shown that these viruses have neurotropic characteristics, and their molecular mimicry can induce inflammatory demyelinating neuropathy. Herein, we describe a case of a GBS in an 85-year-old patient infected with SARS-CoV-2, manifested with acute progressive symmetric ascending quadriparesis, urinary dysautonomia, and dysphagia, who responded well to treatment with intravenous human immunoglobulin.
Keywords: covid-19; guillain barre syndrome; neurotropic virus; viral infections; viral mimicry.