tetano
Editor, Senior Moderator
Cureus
. 2022 Mar 3;14(3):e22790.
doi: 10.7759/cureus.22790. eCollection 2022 Mar.
New-Onset Type 1 Diabetes in Children With SARS-CoV-2 Infection
Shashikanth Ambati[SUP] 1 [/SUP], Maya Mihic[SUP] 2 [/SUP], David Charles Rosario[SUP] 2 [/SUP], Javier Sanchez[SUP] 1 [/SUP], Adnan Bakar[SUP] 1 [/SUP]
Affiliations
Abstract
There has been a worldwide increase in cases of diabetic ketoacidosis in both adults and children with diabetes during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. This can be multifactorial: delayed care due to reduced medical services, fear of approaching hospitals, or SARS-CoV-2 infection itself. It is well-known that infection is an important trigger for diabetic ketoacidosis in children with type 1 or type 2 diabetes mellitus, but little is known whether SARS-CoV-2 infection can trigger diabetic ketoacidosis and new-onset diabetes mellitus in a child with no previous history of diabetes mellitus. The association of SARS-CoV-2 as a trigger for new-onset diabetes requires further investigation, as the incidence of diabetes is steadily rising in the pediatric population during the pandemic. This case report explores two cases where children present in diabetic ketoacidosis with concurrent SARS-CoV-2 infection and no known history of type 1 diabetes mellitus.
Keywords: covid-19; diabetic ketoacidosis (dka); pediatric endocrinology; pediatric intensive care unit (picu); type 1 diabetes mellitus.
. 2022 Mar 3;14(3):e22790.
doi: 10.7759/cureus.22790. eCollection 2022 Mar.
New-Onset Type 1 Diabetes in Children With SARS-CoV-2 Infection
Shashikanth Ambati[SUP] 1 [/SUP], Maya Mihic[SUP] 2 [/SUP], David Charles Rosario[SUP] 2 [/SUP], Javier Sanchez[SUP] 1 [/SUP], Adnan Bakar[SUP] 1 [/SUP]
Affiliations
- PMID: 35382205
- PMCID: PMC8976287
- DOI: 10.7759/cureus.22790
Abstract
There has been a worldwide increase in cases of diabetic ketoacidosis in both adults and children with diabetes during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. This can be multifactorial: delayed care due to reduced medical services, fear of approaching hospitals, or SARS-CoV-2 infection itself. It is well-known that infection is an important trigger for diabetic ketoacidosis in children with type 1 or type 2 diabetes mellitus, but little is known whether SARS-CoV-2 infection can trigger diabetic ketoacidosis and new-onset diabetes mellitus in a child with no previous history of diabetes mellitus. The association of SARS-CoV-2 as a trigger for new-onset diabetes requires further investigation, as the incidence of diabetes is steadily rising in the pediatric population during the pandemic. This case report explores two cases where children present in diabetic ketoacidosis with concurrent SARS-CoV-2 infection and no known history of type 1 diabetes mellitus.
Keywords: covid-19; diabetic ketoacidosis (dka); pediatric endocrinology; pediatric intensive care unit (picu); type 1 diabetes mellitus.