tetano
Editor, Senior Moderator
Cureus
. 2023 Dec 27;15(12):e51189.
doi: 10.7759/cureus.51189. eCollection 2023 Dec. Monitoring SARS-CoV-2 Viral Load and CD4+ T-cell Count After ART in a Patient Diagnosed With AIDS Following SARS-CoV-2 Infection: A Case Report
Yasuhiro Umekage[SUP] 1 [/SUP], Mayumi Hatayama[SUP] 2 [/SUP], Akari Yagita[SUP] 3 [/SUP], Kiichi Nitanai[SUP] 3 [/SUP], Hiraku Yanada[SUP] 3 [/SUP], Ryota Shigaki[SUP] 3 [/SUP], Yoshinori Minami[SUP] 3 [/SUP], Takaaki Sasaki[SUP] 3 [/SUP]
Affiliations
We describe the case of a 36-year-old man diagnosed with human immunodeficiency virus (HIV) following prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia. The patient had a complication of pneumocystis pneumonia. Upon initiating highly active antiretroviral therapy, we monitored HIV RNA levels, CD4+ T-cell count, SARS-CoV-2 viral load, and IgG antibodies against SARS-CoV-2. At 167 days post SARS-CoV-2 diagnosis, the patient's CD4+ T-cell count increased to 180 cells/μL. IgG antibodies against SARS-CoV-2 were undetectable despite a decreased SARS-CoV-2 viral load. HIV screening is necessary in cases of prolonged SARS-CoV-2 pneumonia or persistent SARS-CoV-2 shedding. When diagnosed with HIV infection, it is advisable to consider the possibility of pneumocystis pneumonia.
Keywords: acquired immune deficiency syndrome (aids); aids; hiv; pneumocystis pneumonia; sars-cov-2.
. 2023 Dec 27;15(12):e51189.
doi: 10.7759/cureus.51189. eCollection 2023 Dec. Monitoring SARS-CoV-2 Viral Load and CD4+ T-cell Count After ART in a Patient Diagnosed With AIDS Following SARS-CoV-2 Infection: A Case Report
Yasuhiro Umekage[SUP] 1 [/SUP], Mayumi Hatayama[SUP] 2 [/SUP], Akari Yagita[SUP] 3 [/SUP], Kiichi Nitanai[SUP] 3 [/SUP], Hiraku Yanada[SUP] 3 [/SUP], Ryota Shigaki[SUP] 3 [/SUP], Yoshinori Minami[SUP] 3 [/SUP], Takaaki Sasaki[SUP] 3 [/SUP]
Affiliations
- PMID: 38283513
- PMCID: PMC10817777
- DOI: 10.7759/cureus.51189
We describe the case of a 36-year-old man diagnosed with human immunodeficiency virus (HIV) following prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia. The patient had a complication of pneumocystis pneumonia. Upon initiating highly active antiretroviral therapy, we monitored HIV RNA levels, CD4+ T-cell count, SARS-CoV-2 viral load, and IgG antibodies against SARS-CoV-2. At 167 days post SARS-CoV-2 diagnosis, the patient's CD4+ T-cell count increased to 180 cells/μL. IgG antibodies against SARS-CoV-2 were undetectable despite a decreased SARS-CoV-2 viral load. HIV screening is necessary in cases of prolonged SARS-CoV-2 pneumonia or persistent SARS-CoV-2 shedding. When diagnosed with HIV infection, it is advisable to consider the possibility of pneumocystis pneumonia.
Keywords: acquired immune deficiency syndrome (aids); aids; hiv; pneumocystis pneumonia; sars-cov-2.